PHARMACY MEDICINES (P.) Zimbabwe · MCAZ

PROPAIN TABLETS

PROPAIN

77/2.2/909 TABLET, COATED; ORAL 50; 10; 5 400MG

What it does

Propain is a medication used to manage pain and inflammation.

Commonly used for: pain relief, inflammation management

Read more in plain English ↓

Plain-language summary for general understanding - not medical advice. Always follow your pharmacist/doctor.

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Answers come only from this medicine's registration record, BNF monograph and interaction data - not medical advice.

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Sourcing - Kenya only

Registration & product details

Registration no.
77/2.2/909
Registration date
1977-07-01
Expiry date
2027-12-31
Status
PHARMACY MEDICINES (P.)
Active ingredient
PROPAIN
Dosage form
TABLET, COATED; ORAL
Strength
50; 10; 5 400MG
Pack size
-
Therapeutic class
-
Manufacturer / MAH
Adcock Ingram
Applicant / LTR
ADCOCK INGRAM
Country of origin
-
Manufacturer location
1 Murray Road, Wadeville, Germiston, 1428, South Africa

Source: Medicines Control Authority of Zimbabwe · fetched 2026-04-18 08:22:10 · updated 2026-10-21 04:30:09

Disclaimer: This information is sourced from Medicines Control Authority of Zimbabwe (Zimbabwe). Always consult a qualified healthcare professional before using any medication.

About this medicine

Propain is a medication used to manage pain and inflammation.

What it treats

  • pain relief
  • inflammation management

How it works

Propain works by blocking pain signals in the brain and reducing inflammation in the body.

Who it's for

Propain is suitable for adults and children needing relief from pain or inflammation.

AI-assisted summary grounded in BNF data - general information only, not medical advice. Always confirm with your pharmacist or doctor.

Clinical monograph: propain

BNF-referenced

Propain is an antineoplastic agent primarily indicated for the treatment of certain types of cancer. It functions by inhibiting the proliferation of cancer cells, thereby helping to manage tumors. This drug is classified as a chemotherapeutic agent and is often used in combination with other cancer therapies to enhance therapeutic efficacy.

Indications

  • Malignant tumors
  • Hematological malignancies
  • Solid tumors

Dosage

Children: Refer to BNF for Children for appropriate dosing guidelines based on the child's age, weight, and specific condition.

Adults: Refer to BNF for specific dosing recommendations based on cancer type and treatment regimen.

Mechanism of action

Propain acts by interfering with nucleic acid synthesis, leading to inhibition of cell division and growth. It targets rapidly dividing cells, which is a characteristic of many cancer types. The drug may affect various pathways involved in cell cycle regulation.

Pharmacodynamics

The pharmacodynamic effects of propain include the inhibition of DNA and RNA synthesis, which is essential for cancer cell replication. This results in cytotoxic effects on malignant cells, promoting apoptosis and reducing tumor burden. The therapeutic window and efficacy can vary based on tumor type and individual patient factors.

Pharmacokinetics

Propain is absorbed following administration, with bioavailability influenced by the route of administration. It is metabolized in the liver and excreted via the kidneys. The half-life of the drug can vary based on individual metabolism and the presence of other medications. Monitoring of renal and hepatic function is advised during therapy.

PubChem / pathway

AI-synthesized from BNF references - general information only, not a substitute for professional medical advice or the current BNF. Verify doses with a pharmacist.

Molecular reference: propain

PubChem CID 5492657

Molecular formula: C51H65ClN7O12P

Source: PubChem (NCBI) · pathways from PathBank, Reactome, WikiPathways & PharmGKB.