SANISCOPE
Sodium Perborate Monohydrate 50 w/v
What it does
Perborate is a chemical compound often used in cleaning and whitening products, particularly for teeth.
Commonly used for: tooth whitening, cleaning agents
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Sourcing - Kenya onlyRegistration & product details
Source: Tanzania Medicines and Medical Devices Authority · fetched 2026-03-11 23:38:56 · updated 2026-10-19 03:00:44
About this medicine
Perborate is a chemical compound often used in cleaning and whitening products, particularly for teeth.
What it treats
- tooth whitening
- cleaning agents
How it works
Perborate releases oxygen when it comes into contact with water, which helps to remove stains and whiten surfaces.
Who it's for
Adults and children who need teeth whitening or cleaning products.
AI-assisted summary grounded in BNF data - general information only, not medical advice. Always confirm with your pharmacist or doctor.
Clinical monograph: perborate
BNF-referencedPerborate is a chemical compound that is commonly used as a bleaching agent and an oxidizing agent in various applications, including laundry detergents and oral hygiene products. It releases hydrogen peroxide when dissolved in water, which contributes to its antibacterial and whitening properties. Perborate can exist in various forms, including sodium perborate, which is the most commonly used form in commercial products.
Indications
- Oral hygiene
- Bleaching agent in dental procedures
- Laundry and fabric cleaning
Dosage
Children: Refer to specific product guidelines or consult a healthcare professional for appropriate pediatric dosing.
Adults: Refer to specific product guidelines or consult a healthcare professional for appropriate dosing.
Mechanism of action
Perborate acts primarily as an oxidizing agent. Upon dissolution, it decomposes to release hydrogen peroxide, which exerts its antimicrobial effect by producing reactive oxygen species that damage cellular components, including lipids, proteins, and nucleic acids, leading to cell death. The release of hydrogen peroxide also contributes to its bleaching effects by breaking down chromophores in colored substances, thereby whitening them.
Pharmacodynamics
The pharmacodynamics of perborate is closely tied to its release of hydrogen peroxide. The antimicrobial activity is concentration-dependent, with higher concentrations showing greater effectiveness against a broad spectrum of bacteria. In the context of dentistry, it is used for its ability to oxidize and neutralize organic matter, which can help in the management of oral infections and improve oral hygiene.
Pharmacokinetics
Perborate does not have a defined pharmacokinetic profile in humans, as it is primarily used topically or in dental applications and is not systemically absorbed in significant amounts. When used in oral hygiene products, it may be partially broken down in the oral cavity, releasing hydrogen peroxide, which can then exert local effects. Its systemic absorption is minimal, and it is generally considered safe for use in the concentrations found in commercial products.
Pregnancy
There is limited information on the safety of perborate during pregnancy. It is advisable to avoid its use unless deemed necessary by a healthcare provider.
Breast-feeding
Limited data is available regarding the excretion of perborate in breast milk. Caution is advised when using this substance while breastfeeding.
Storage
Store in a cool, dry place away from direct sunlight. Keep container tightly closed and out of reach of children.
AI-synthesized from BNF references - general information only, not a substitute for professional medical advice or the current BNF. Verify doses with a pharmacist.
Molecular reference: perborate
PubChem CID 5460515Molecular formula: B2H4O8-2
Source: PubChem (NCBI) · pathways from PathBank, Reactome, WikiPathways & PharmGKB.