Sanome 1000
Cefpirome Sulphate equivalent to anhydrous Cefpirome 1000 mg
What it does
Cefpirome is an antibiotic used to treat various bacterial infections.
Commonly used for: bacterial infections, infections of the skin, infections of the lungs (pneumonia), infections of the urinary tract
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Sourcing - Kenya onlyRegistration & product details
Source: Tanzania Medicines and Medical Devices Authority · fetched 2026-03-11 23:54:02 · updated 2026-09-24 03:00:47
About this medicine
Cefpirome is an antibiotic used to treat various bacterial infections.
What it treats
- bacterial infections
- infections of the skin
- infections of the lungs (pneumonia)
- infections of the urinary tract
How it works
Cefpirome works by killing bacteria or stopping their growth, helping your body to fight off the infection.
Who it's for
Cefpirome is for adults and children who have certain types of bacterial infections.
AI-assisted summary grounded in BNF data - general information only, not medical advice. Always confirm with your pharmacist or doctor.
Clinical monograph: cefpirome
BNF-referencedCefpirome is a fourth-generation cephalosporin antibiotic known for its broad-spectrum activity against both Gram-positive and Gram-negative bacteria. It is particularly effective against organisms that are resistant to earlier generations of cephalosporins. Cefpirome is used in the treatment of serious infections caused by susceptible bacteria, including respiratory tract infections, urinary tract infections, and sepsis.
Indications
- Severe bacterial infections
- Respiratory tract infections
- Urinary tract infections
- Sepsis
Dosage
Children: Refer to BNF for Children for appropriate paediatric dosing guidelines.
Adults: The usual adult dose is 1–2 g administered intravenously every 8–12 hours, depending on the severity of the infection and the susceptibility of the organism.
Mechanism of action
Cefpirome is a β-lactam (cephalosporin) antibiotic that binds to penicillin-binding proteins (PBPs) and inhibits peptidoglycan cross-linking in bacterial cell-wall synthesis. This action leads to the disruption of the bacterial cell wall, ultimately resulting in cell lysis and death.
Pharmacodynamics
Cefpirome exhibits time-dependent bactericidal activity, which means that its efficacy is related to the duration of time that the drug concentration remains above the minimum inhibitory concentration (MIC) for the target bacteria. It has a broad spectrum of activity, including coverage against certain multi-drug resistant strains. The drug is generally well-tolerated, but potential adverse effects can include allergic reactions, gastrointestinal disturbances, and impacts on renal function.
Pharmacokinetics
Cefpirome is well absorbed when administered intravenously, and it demonstrates a volume of distribution that allows for good penetration into tissues and body fluids. The drug is primarily excreted unchanged via the kidneys, which means that renal function can significantly affect its clearance. The half-life of cefpirome is approximately 2 hours, necessitating multiple daily doses for effective therapy.
Pregnancy
Cefpirome should only be used in pregnancy if the benefits outweigh the risks, as there is limited data on its safety.
Breast-feeding
Cefpirome is excreted in breast milk, and caution should be exercised when administering to nursing mothers.
Storage
Store in a cool, dry place away from light. Protect from moisture.
AI-synthesized from BNF references - general information only, not a substitute for professional medical advice or the current BNF. Verify doses with a pharmacist.
Molecular reference: cefpirome
PubChem CID 5479539Molecular formula: C22H22N6O5S2
Mechanism of action
Cefpirome is a β-lactam (cephalosporin) antibiotic that binds penicillin-binding proteins (PBPs) and inhibits peptidoglycan cross-linking in bacterial cell-wall synthesis.
Source: PubChem (NCBI) · pathways from PathBank, Reactome, WikiPathways & PharmGKB.
This drug in other countries
The same active ingredient registered across other registries we cover - including different brands.