International reference: 6 US FDA recalls for this ingredient
Presence of foreign substance: small metallic particles in chewable tablets. (antacid)
CGMP Deviations: product held outside appropriate storage temperature conditions. (antacid)
Presence of foreign substance: small metallic particles in chewable tablets. (antacid)
Presence of Foreign Substance: The foreign material is primarily comprised of glass mineral wool. (antacid)
Presence of foreign substance: small metallic particles in chewable tablets. (antacid)
Defective Container: Confirmed customer compliant of small holes or cracks in the foil of blister packs. (antacid)
US-market enforcement records (OpenFDA), shown for reference - not specific to this product in Kenya.
SILOXOGENE GEL
ANTACID AND ANTIFLATULENT
What it does
Antacids are medicines that help relieve heartburn and indigestion by neutralizing stomach acid.
Commonly used for: heartburn, indigestion, acid reflux
Read more in plain English ↓Plain-language summary for general understanding - not medical advice. Always follow your pharmacist/doctor.
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Source: Pharmacy and Poisons Board · fetched 2026-01-28 21:57:40 · updated 2026-03-23 04:42:47
About antacid
Antacids are medicines that help relieve heartburn and indigestion by neutralizing stomach acid.
What it treats
- heartburn
- indigestion
- acid reflux
How it works
Antacids work by reducing the acidity in the stomach, which helps to relieve discomfort.
Who it's for
Antacids are suitable for adults and children who experience discomfort from excess stomach acid.
AI-assisted summary grounded in BNF data - general information only, not medical advice. Always confirm with your pharmacist or doctor.
About antiflatulent
Antiflatulents are medications that help reduce gas in the digestive system, making you feel more comfortable.
What it treats
- excess gas (flatulence)
- bloating
- indigestion
How it works
These medications work by breaking down gas bubbles in the stomach and intestines, which helps relieve discomfort.
Who it's for
Antiflatulents are suitable for adults and children experiencing gas-related discomfort.
AI-assisted summary grounded in BNF data - general information only, not medical advice. Always confirm with your pharmacist or doctor.
Clinical monograph: antacid
Antacids are a class of medications used to neutralize stomach acid, providing relief from symptoms of heartburn, indigestion, and gastroesophageal reflux disease (GERD). They are commonly composed of compounds such as magnesium, aluminum, calcium, or sodium bicarbonate. By increasing gastric pH, antacids alleviate discomfort associated with excess acid production.
Indications
- Heartburn
- Indigestion
- Gastroesophageal reflux disease (GERD)
- Duodenal ulcers
- Peptic ulcers
Dosage
Children: Refer to BNF for Children for specific dosing guidelines based on age and formulation.
Adults: Refer to BNF for specific dosing guidelines based on formulation and indication.
Mechanism of action
Antacids work by directly neutralizing gastric hydrochloric acid, leading to an increase in gastric pH. This reduction in acidity helps to soothe the gastric mucosa and decrease the symptoms of acid-related disorders. The exact mechanism can vary slightly based on the specific type of antacid used, such as magnesium hydroxide or calcium carbonate.
Pharmacodynamics
The pharmacodynamic effects of antacids are primarily focused on their ability to raise gastric pH, thereby reducing acid-related symptoms. The onset of action is typically rapid, often within minutes, and the effects can last for a few hours depending on the formulation and dosage.
Pharmacokinetics
Antacids are generally administered orally and their absorption can vary significantly based on the specific formulation. For example, some antacids are rapidly absorbed into the bloodstream, while others may act locally in the gastrointestinal tract. The onset of action is usually within 30 minutes, with peak effects occurring within 1-2 hours. They are eliminated primarily through renal excretion, with the half-life depending on the specific ingredient used.
Interactions
- antacids+roxadustat: Unknown (decreases exposure)
- antacids+selpercatinib: Unknown (decreases exposure)
- antacids+ulipristal for emergency hormonal contraception: Unknown (decreases efficacy)
Pregnancy
Antacids are generally considered safe during pregnancy; however, specific formulations may contain ingredients that should be avoided. Consult a healthcare professional.
Breast-feeding
Antacids are typically safe during breastfeeding, but it is advisable to consult a healthcare provider for specific recommendations.
Storage
Store in a cool, dry place away from direct sunlight. Keep out of reach of children.
AI-synthesized from BNF references - general information only, not a substitute for professional medical advice or the current BNF. Verify doses with a pharmacist.
Clinical monograph: antiflatulent
Antiflatulents are medications designed to alleviate symptoms associated with excessive gas in the gastrointestinal tract. They work by reducing the surface tension of gas bubbles, which helps in their coalescence and subsequent elimination from the body. Commonly used antiflatulents include simethicone, which is widely utilized due to its effectiveness and safety profile.
Indications
- Relief of symptoms associated with excess gas in the gastrointestinal tract
- Bloating
- Flatulence
- Abdominal discomfort
Dosage
Children: Refer to BNF for Children for age-specific dosing recommendations, as they can vary widely depending on the formulation and the child's age.
Adults: Refer to the product-specific guidelines as dosages can vary based on formulation and brand. Generally, doses are taken after meals and at bedtime as needed.
Mechanism of action
Antiflatulents primarily work by altering the surface tension of gas bubbles in the gastrointestinal tract, allowing smaller bubbles to merge into larger ones. This facilitates easier expulsion of gas from the intestines, thereby relieving symptoms of bloating and discomfort. Simethicone, for example, acts by decreasing surface tension, which helps in the coalescence of gas bubbles and promotes their elimination.
Pharmacodynamics
The pharmacodynamic effects of antiflatulents, such as simethicone, include the reduction of gas-related symptoms like bloating, abdominal pain, and discomfort. By decreasing the surface tension of gas bubbles, these agents enhance the efficacy of gas elimination processes in the gastrointestinal tract. They do not alter gastrointestinal motility or digestion, making them a suitable option for symptomatic relief.
Pharmacokinetics
Antiflatulents like simethicone are not absorbed systemically and act locally within the gastrointestinal lumen. They are excreted unchanged in the feces. Due to their local action and minimal absorption, they are considered safe for use in various populations, including children and pregnant women.
Adverse effects
- Nausea
- Diarrhea
- Constipation
- Allergic reactions (rare)
Precautions
- Use with caution in patients with gastrointestinal disorders
- Monitor for any allergic reactions
Pregnancy
Safety during pregnancy has not been established; consult a healthcare provider before use.
Breast-feeding
Consult a healthcare provider before use while breastfeeding.
Storage
Store in a cool, dry place, away from direct sunlight.
Formulations
- Oral tablets
- Chewable tablets
- Liquid suspensions
AI-synthesized from BNF references - general information only, not a substitute for professional medical advice or the current BNF. Verify doses with a pharmacist.