Registered Zambia · ZAMRA

Sitcom tablets

Euphorbia prostrata 100.00 mg

439/002 Tablet, Filmcoated 100.00 mg

What it does

Euphorbia is a plant used in traditional medicine for various health conditions.

Commonly used for: skin conditions, inflammation, pain relief

Read more in plain English ↓

Plain-language summary for general understanding - not medical advice. Always follow your pharmacist/doctor.

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Registration & product details

Registration no.
439/002
Registration date
2024-09-15
Expiry date
2029-09-14
Status
Registered/Compliant
Active ingredient
Euphorbia prostrata 100.00 mg
Dosage form
Tablet, Filmcoated
Strength
100.00 mg
Pack size
-
Therapeutic class
-
Manufacturer / MAH
Panacea Biotech
Country of origin
India
Manufacturer location
Ambala-Chandigarh Highway, Panacea Biotec, Lalru, Chaundheri, Punjab 140501, India

Source: Zambia Medicines Regulatory Authority · fetched 2026-03-12 00:04:38 · updated 2026-09-24 03:36:39

Disclaimer: This information is sourced from Zambia Medicines Regulatory Authority (Zambia). Always consult a qualified healthcare professional before using any medication.

About euphorbia

Euphorbia is a plant used in traditional medicine for various health conditions.

What it treats

  • skin conditions
  • inflammation
  • pain relief

How it works

Euphorbia may have properties that help reduce inflammation and relieve pain.

Who it's for

Adults seeking alternative treatments for mild skin issues and inflammation.

AI-assisted summary grounded in BNF data - general information only, not medical advice. Always confirm with your pharmacist or doctor.

About prostrata

Prostrata is a natural supplement often used to support prostate health.

What it treats

  • prostate enlargement (benign prostatic hyperplasia)
  • urinary issues related to the prostate

How it works

Prostrata may help improve urinary flow and reduce symptoms associated with prostate problems.

Who it's for

Adult men who are experiencing symptoms related to prostate health.

AI-assisted summary grounded in BNF data - general information only, not medical advice. Always confirm with your pharmacist or doctor.

Clinical monograph: euphorbia

Euphorbia is a genus of flowering plants in the family Euphorbiaceae, comprising various species known for their milky latex and diverse forms. Some species are used in traditional medicine for their purported analgesic, anti-inflammatory, and antimicrobial properties. However, many Euphorbia species can be toxic and cause skin irritation or other adverse effects upon contact.

Indications

  • Pain management
  • Inflammation reduction
  • Antimicrobial treatment
  • Potential cancer therapy

Dosage

Children: Dosage for children should be determined by a healthcare professional and should take into account the specific Euphorbia species and its safety profile. Consultation with a healthcare professional is essential.

Adults: Dosage varies widely depending on the specific Euphorbia species and preparation used. Consultation with a healthcare professional and reference to established guidelines is recommended.

Mechanism of action

The pharmacological properties of Euphorbia species often stem from the presence of compounds like diterpenes, flavonoids, and alkaloids, which may interact with various biological pathways. These compounds have been observed to exhibit cytotoxic effects on tumor cells, modulate inflammatory pathways, and influence immune responses. Specific mechanisms may vary among different species within the genus.

Pharmacodynamics

The effects of Euphorbia extracts can vary widely depending on the specific species and the active compounds present. Commonly, these extracts demonstrate anti-inflammatory, analgesic, and potential anticancer activities. Some compounds may inhibit the growth of specific bacteria or fungi, thus exhibiting antimicrobial properties. Additionally, certain Euphorbia species have been studied for their effects on cell proliferation and apoptosis in cancer research.

Pharmacokinetics

The pharmacokinetics of Euphorbia compounds are not well-studied, and available data may vary significantly by species and preparation. Generally, the absorption, distribution, metabolism, and excretion of these compounds can be influenced by their chemical nature and the method of administration. Due to the presence of toxic compounds in some Euphorbia species, careful consideration of dosage and route of administration is essential to avoid adverse effects.

Adverse effects

  • Skin irritation
  • Gastrointestinal upset
  • Allergic reactions
  • Eye irritation

Precautions

  • Use with caution in patients with skin sensitivities
  • Avoid contact with eyes and mucous membranes
  • May be harmful if ingested in large quantities

Pregnancy

Not enough reliable information is available regarding the safety of Euphorbia in pregnancy. It is advisable to avoid use unless prescribed by a healthcare professional.

Breast-feeding

There is insufficient information on the excretion of Euphorbia into breast milk. Caution is recommended.

Storage

Store in a cool, dry place away from direct sunlight. Keep out of reach of children.

Formulations

  • Topical preparations (creams, ointments)
  • Liquid extracts
  • Powdered forms

AI-synthesized from BNF references - general information only, not a substitute for professional medical advice or the current BNF. Verify doses with a pharmacist.

Clinical monograph: prostrata

Prostrata, commonly known as saw palmetto, is a herbal supplement derived from the fruit of the Serenoa repens plant. It is widely used for its potential benefits in managing benign prostatic hyperplasia (BPH) and for its purported ability to support urinary function. The extract is rich in fatty acids and phytosterols, which are believed to contribute to its therapeutic effects. Prostrata is often considered as an alternative treatment for patients seeking relief from urinary symptoms associated with an enlarged prostate.

Indications

  • Benign prostatic hyperplasia (BPH)
  • Urinary symptoms related to prostate enlargement
  • Supportive treatment for urinary function

Dosage

Children: There is limited evidence to support the use of prostrata in paediatric populations. Refer to clinical guidelines or consult a

Adults: Refer to appropriate clinical guidelines or product-specific recommendations as no specific dosing information is provided.

Mechanism of action

Prostrata is thought to exert its effects primarily through inhibition of 5-alpha-reductase, an enzyme responsible for the conversion of testosterone to dihydrotestosterone (DHT). Elevated levels of DHT are associated with the development of BPH. By reducing DHT levels, prostrata may help alleviate symptoms such as urinary frequency, urgency, and nocturia. Additionally, prostrata may have anti-inflammatory properties that contribute to its effectiveness in managing prostate health.

Pharmacodynamics

The pharmacodynamics of prostrata involve its action on androgen metabolism and inflammatory pathways. The inhibition of 5-alpha-reductase leads to a decrease in DHT production, which may help shrink prostate tissue and improve urinary flow. Furthermore, the anti-inflammatory effects may assist in reducing prostate swelling and discomfort. However, the clinical significance of these actions in terms of symptom relief and prostate size reduction can vary among individuals.

Pharmacokinetics

The pharmacokinetics of prostrata have not been extensively studied through rigorous clinical trials. However, it is believed to be absorbed through the gastrointestinal tract, with peak plasma concentrations occurring several hours after ingestion. The elimination half-life is not well defined, and individual metabolism may vary based on factors such as age, health status, and concurrent medications. The bioavailability of the active compounds in prostrata can be influenced by the formulation and preparation of the extract.

Pregnancy

There is insufficient data on the safety of prostrata in pregnancy. Use with caution and only if the potential benefit justifies the potential risk to the fetus.

Breast-feeding

It is unknown whether prostrata is excreted in human milk. Caution is advised when administering to nursing mothers.

Storage

Store at room temperature, away from moisture and heat. Keep out of reach of children.

AI-synthesized from BNF references - general information only, not a substitute for professional medical advice or the current BNF. Verify doses with a pharmacist.

This drug in other countries

The same active ingredient registered across other registries we cover - including different brands.