What it does
Proanthrocyanidin is a natural compound found in various plants, known for its antioxidant properties.
Commonly used for: improving blood circulation, supporting heart health, reducing inflammation, helping with urinary tract health (cystitis)
Read more in plain English ↓Plain-language summary for general understanding - not medical advice. Always follow your pharmacist/doctor.
Ask about this medicine
Answers come only from this medicine's registration record, BNF monograph and interaction data - not medical advice.
Medicine sourcing is available in Kenya only. We don't sell or dispense medicines - licensed pharmacies do.
Sourcing - Kenya onlyRegistration & product details
Source: Pharmacy and Medicines Regulatory Authority · fetched 2026-04-21 17:37:39 · updated 2026-09-29 04:33:04
About this medicine
Proanthrocyanidin is a natural compound found in various plants, known for its antioxidant properties.
What it treats
- improving blood circulation
- supporting heart health
- reducing inflammation
- helping with urinary tract health (cystitis)
How it works
Proanthrocyanidin works by neutralizing harmful free radicals in the body and promoting better blood flow.
Who it's for
It is suitable for adults looking to support their overall health and wellness.
AI-assisted summary grounded in BNF data - general information only, not medical advice. Always confirm with your pharmacist or doctor.
Clinical monograph: proanthrocyanadin
Proanthocyanidins are a class of polyphenolic compounds found in a variety of plants, particularly in the bark of trees, fruits, and leaves. They are known for their antioxidant properties and potential health benefits, including improving cardiovascular health and reducing inflammation. Proanthocyanidins are commonly derived from sources such as grape seeds, pine bark, and cranberries.
Indications
- Antioxidant support
- Cardiovascular health
- Chronic inflammation
- Urinary tract health
- Skin health
- Weight management
Dosage
Children: Refer to established guidelines and resources as specific dosing can vary based on formulation and intended use.
Adults: Refer to established guidelines and resources as specific dosing can vary based on formulation and intended use.
Mechanism of action
Proanthocyanidins exert their effects primarily through the inhibition of oxidative stress and the modulation of various signaling pathways. They scavenge free radicals, thereby preventing cellular damage. Additionally, they may enhance nitric oxide production, improving endothelial function and promoting vasodilation. Proanthocyanidins have also been shown to inhibit the activity of certain enzymes involved in inflammatory processes.
Pharmacodynamics
The pharmacodynamics of proanthocyanidins involve their capacity to interact with cellular receptors and enzymes. They are known to possess anti-inflammatory, anti-viral, and anti-cancer properties. Their antioxidant activities contribute to the protection of cells against oxidative damage, which is a contributing factor in many chronic diseases. The bioavailability of these compounds can vary, influencing their therapeutic effects.
Pharmacokinetics
Proanthocyanidins are generally poorly absorbed in the gastrointestinal tract due to their large molecular size and complex structures. They undergo extensive metabolism in the liver and may be converted into smaller phenolic acids that can be more effectively absorbed. The elimination of proanthocyanidins occurs primarily through the urine, with some metabolites being excreted in feces. The half-life of these compounds can vary based on the specific type of proanthocyanidin and the individual's metabolic capacity.
Pregnancy
There is insufficient data on the safety of proanthocyanidins in pregnancy. Caution is advised.
Breast-feeding
Limited data is available on the excretion of proanthocyanidins in human milk. Caution is recommended.
Storage
Store in a cool, dry place away from direct sunlight. Keep out of reach of children.
Formulations
- Capsules
- Tablets
- Powder
- Liquid extract
AI-synthesized from BNF references - general information only, not a substitute for professional medical advice or the current BNF. Verify doses with a pharmacist.