Sulfanor 33%
Sulfamidine Sodium 33 mg/ml
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Sourcing - Kenya onlyRegistration & product details
Source: Zambia Medicines Regulatory Authority · fetched 2026-10-19 03:40:05
Molecular reference: sulfamidine
PubChem CID 5327Molecular formula: C12H14N4O2S
Mechanism of action
Sulfonamides inhibit the enzymatic conversion of pteridine and p-aminobenzoic acid (PABA) to dihydropteroic acid by competing with PABA for binding to dihydrofolate synthetase, an intermediate of tetrahydrofolic acid (THF) synthesis. THF is required for the synthesis of purines and dTMP and inhibition of its synthesis inhibits bacterial growth. Pyrimethamine and trimethoprim inhibit dihydrofolate reductase, another step in THF synthesis, and therefore act synergistically with the sulfonamides.
Pharmacodynamics
Sulfamethazine is a sulfonamide drug that inhibits bacterial synthesis of dihydrofolic acid by competing with para-aminobenzoic acid (PABA) for binding to dihydropteroate synthetase (dihydrofolate synthetase). Sulfamethazine is bacteriostatic in nature. Inhibition of dihydrofolic acid synthesis decreases the synthesis of bacterial nucleotides and DNA.
Source: PubChem (NCBI) · pathways from PathBank, Reactome, WikiPathways & PharmGKB.
This drug in other countries
The same active ingredient registered across other registries we cover - including different brands.
- ADRENALINE INJ 1MG/ML 1ML · Nairobi Pharmaceuticals
- ADVOCATE (FOR CATS) SOLUTION · Bayer
- ATRAPURE 2.5ML INJECTION · Nairobi Enterprises
- ATROMED INJECTION · Dawa
- ATROPINE · Reddys Pharma
- ATROPINE SULPHATE INJ. 0.6MG/ML 1ML · Nairobi Pharmaceuticals