Registered Zambia · ZAMRA

Sulfanor 33%

Sulfamidine Sodium 33 mg/ml

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Registration & product details

Registration no.
ZAMRA-VM-26-441
Registration date
2026-10-15
Expiry date
2031-10-14
Status
Registered/Compliant
Active ingredient
Sulfamidine Sodium 33 mg/ml
Strength
-
Pack size
-
Therapeutic class
-
Applicant / LTR
JUBAILI AGROTEC LIMITED
Country of origin
China

Source: Zambia Medicines Regulatory Authority · fetched 2026-10-19 03:40:05

Disclaimer: This information is sourced from Zambia Medicines Regulatory Authority (Zambia). Always consult a qualified healthcare professional before using any medication.

Molecular reference: sulfamidine

PubChem CID 5327

Molecular formula: C12H14N4O2S

Mechanism of action

Sulfonamides inhibit the enzymatic conversion of pteridine and p-aminobenzoic acid (PABA) to dihydropteroic acid by competing with PABA for binding to dihydrofolate synthetase, an intermediate of tetrahydrofolic acid (THF) synthesis. THF is required for the synthesis of purines and dTMP and inhibition of its synthesis inhibits bacterial growth. Pyrimethamine and trimethoprim inhibit dihydrofolate reductase, another step in THF synthesis, and therefore act synergistically with the sulfonamides.

Pharmacodynamics

Sulfamethazine is a sulfonamide drug that inhibits bacterial synthesis of dihydrofolic acid by competing with para-aminobenzoic acid (PABA) for binding to dihydropteroate synthetase (dihydrofolate synthetase). Sulfamethazine is bacteriostatic in nature. Inhibition of dihydrofolic acid synthesis decreases the synthesis of bacterial nucleotides and DNA.

Source: PubChem (NCBI) · pathways from PathBank, Reactome, WikiPathways & PharmGKB.

This drug in other countries

The same active ingredient registered across other registries we cover - including different brands.