ZINCOFER CAPSULES
HAEMATINIC CAPSULES
What it does
Haematinics are substances that help increase the amount of iron in your body, which is important for making red blood cells.
Commonly used for: iron deficiency anemia, low iron levels
Read more in plain English ↓Plain-language summary for general understanding - not medical advice. Always follow your pharmacist/doctor.
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Source: Pharmacy and Poisons Board · fetched 2026-01-28 20:51:08 · updated 2026-07-26 11:41:45
About this medicine
Haematinics are substances that help increase the amount of iron in your body, which is important for making red blood cells.
What it treats
- iron deficiency anemia
- low iron levels
How it works
Haematinics work by providing your body with the iron it needs to produce healthy red blood cells.
Who it's for
These are typically for people with low iron levels or those who have trouble absorbing enough iron from their diet.
AI-assisted summary grounded in BNF data - general information only, not medical advice. Always confirm with your pharmacist or doctor.
Clinical monograph: haematinic
Haematinics are agents that enhance the production of hemoglobin and red blood cells, primarily used to treat or prevent anemia caused by iron deficiency or other hematological conditions. They play a critical role in managing conditions associated with inadequate hemoglobin levels, such as iron-deficiency anemia, megaloblastic anemia, and anemia of chronic disease. Haematinics include iron supplements, vitamin B12, and folic acid, which are essential for erythropoiesis.
Indications
- Iron-deficiency anemia
- Megaloblastic anemia
- Anemia of chronic disease
- Pregnancy-related anemia
- Nutritional deficiencies
Dosage
Adults: Refer to the relevant BNF text for specific dosing guidelines, as doses will
Mechanism of action
Iron supplements, as a key component of haematinics, function by replenishing iron stores in the body, which is crucial for hemoglobin synthesis. Iron is incorporated into hemoglobin within red blood cells, facilitating oxygen transport. Vitamin B12 and folic acid are vital for DNA synthesis and cell division, playing significant roles in the maturation of red blood cells in the bone marrow. Their deficiency can lead to megaloblastic anemia, characterized by the production of large, dysfunctional red blood cells.
Pharmacodynamics
The pharmacodynamic effects of haematinics pertain to their ability to improve hemoglobin concentrations and overall erythropoiesis. Iron supplements increase serum ferritin levels and transferrin saturation, promoting better oxygen-carrying capacity of the blood. Vitamin B12 and folic acid enhance the proliferation and maturation of erythroid progenitor cells, ensuring a healthy red blood cell turnover and prevent macrocytic anemia.
Pharmacokinetics
Iron is absorbed primarily in the duodenum and proximal jejunum, with absorption influenced by dietary factors and the form of iron administered (ferrous vs ferric). Once absorbed, iron is transported in the bloodstream bound to transferrin, and stored in the liver as ferritin. Vitamin B12 is absorbed in the ileum and requires intrinsic factor for optimal absorption, while folic acid is absorbed in the jejunum. The half-lives of these agents vary, with dietary iron having a half-life of several hours to days in the body, while vitamin B12 can remain stored in the liver for several years.
Contra-indications
- Hypersensitivity to any component of the formulation
- Hemochromatosis
- Hemosiderosis
- Uncontrolled hypertension
Adverse effects
- Gastrointestinal disturbances (nausea, vomiting, constipation, diarrhea)
- Abdominal pain
- Metallic taste
- Dark stools
- Allergic reactions (rash, itching)
- Iron overload (in cases of excessive dosage)
Interactions
- Antacids may reduce the absorption of iron
- Certain antibiotics (like tetracyclines and fluoroquinolones) may have reduced effectiveness when taken with iron
- Vitamin C can enhance iron absorption
- Foods high in calcium or phosphates may inhibit iron absorption
Precautions
- Monitor hemoglobin levels during treatment to avoid iron overload
- Use with caution in patients with liver disease
- Consider potential interactions with other medications
- Assess dietary intake to avoid excessive iron supplementation
Pregnancy
Iron supplementation is commonly recommended during pregnancy to prevent or treat iron deficiency anemia. Dosage and specific formulations should be guided by clinical evaluation.
Breast-feeding
Iron can be excreted in breast milk, but supplementation is typically safe and may be necessary for breastfeeding mothers, especially if they are anemic. Consultation with a healthcare provider is advised.
Storage
Store in a cool, dry place, away from moisture and direct sunlight. Keep out of reach of children.
Formulations
- Oral tablets
- Liquid formulations
- Intravenous preparations
AI-synthesized from BNF references - general information only, not a substitute for professional medical advice or the current BNF. Verify doses with a pharmacist.
This drug in other countries
The same active ingredient registered across other registries we cover - including different brands.