roflumilast brands
2 registered brands containing roflumilast in Kenya.
Roflumilast
PubChem CID 449193Molecular formula: C17H14Cl2F2N2O3
Roflumilast and its active metabolite (roflumilast N-oxide) are inhibitors of PDE4. Roflumilast and roflumilast N-oxide inhibition of PDE4 (a major cyclic 3′,5′-adenosine monophosphate (cyclic AMP) metabolizing enzyme) activity leads to accumulation of intracellular cyclic AMP. The specific mechanism(s) by which roflumilast exerts its therapeutic action is not well defined.
Source: PubChem (NCBI) · compound 449193