AIVLOSIN
Tyvalosin Tartrate 625 mg/gm
What it does
Tyvalosin is an antibiotic
Commonly used for: infections caused by bacteria
Read more in plain English ↓Plain-language summary for general understanding - not medical advice. Always follow your pharmacist/doctor.
Ask about this medicine
Answers come only from this medicine's registration record, BNF monograph and interaction data - not medical advice.
Medicine sourcing is available in Kenya only. We don't sell or dispense medicines - licensed pharmacies do.
Sourcing - Kenya onlyRegistration & product details
Source: Zambia Medicines Regulatory Authority · fetched 2026-04-14 13:57:08 · updated 2026-10-19 03:33:06
About this medicine
Tyvalosin is an antibiotic
What it treats
- infections caused by bacteria
How it works
by stopping the growth of bacteria
Who it's for
people with bacterial infections
AI-assisted summary grounded in BNF data - general information only, not medical advice. Always confirm with your pharmacist or doctor.
Clinical monograph: tyvalosin
Tyvalosin is a macrolide antibiotic used to treat various infections caused by bacteria. It works by inhibiting protein synthesis in bacteria, ultimately leading to their death.
Indications
- Community-acquired pneumonia
- Skin and soft tissue infections
- Pharyngitis and tonsillitis
Dosage
Children: Refer to the BNF for Children for specific dosage recommendations in pediatric patients.
Adults: Typical dosage is 200-400 mg every 12 hours for 7-14 days, but the exact dosage and duration may vary depending on the specific infection and patient factors.
Mechanism of action
Inhibits protein synthesis by binding to the bacterial 50S ribosomal subunit, thereby preventing peptide bond formation.
Pharmacodynamics
The antimicrobial activity of tyvalosin is directed against a wide range of Gram-positive and Gram-negative bacteria. It is most effective against bacteria with a 50S ribosomal subunit, such as Staphylococcus aureus and Streptococcus pneumoniae.
Pharmacokinetics
Tyvalosin is absorbed orally and reaches peak plasma concentrations within 2-4 hours. It is extensively distributed to tissues and has a half-life of approximately 6-8 hours. It is primarily excreted in the feces, with minimal renal excretion.
Contra-indications
- Hypersensitivity to tyvalosin or other macrolide antibiotics
- Pregnancy (first trimester) and lactation
- Renal impairment (dose adjustment recommended)
Adverse effects
- Nausea and vomiting
- Diarrhea
- Abdominal pain
- Headache
- Rash
- Hypersensitivity reactions
Interactions
- Warfarin: Increased risk of bleeding
- Rifampicin: Reduced efficacy of tyvalosin
- Cyclosporin: Increased risk of nephrotoxicity
Precautions
- Renal impairment: Dose adjustment recommended
- Hepatic impairment: Dose adjustment recommended
- Pregnancy and lactation: Use with caution
- Children: Use with caution in children under 12 years old
Pregnancy
Use with caution; safety not established in the first trimester.
Breast-feeding
Use with caution; excretion in breast milk unknown.
Storage
Store in a cool, dry place; protect from light.
Formulations
- Tablets: 100mg, 200mg
- Granules for oral suspension: 50mg/5mL, 100mg/5mL
AI-synthesized from BNF references - general information only, not a substitute for professional medical advice or the current BNF. Verify doses with a pharmacist.
This drug in other countries
The same active ingredient registered across other registries we cover - including different brands.