What it does
Saccharomyces is a type of yeast used as a dietary supplement to support digestive health.
Commonly used for: digestive issues, diarrhea, irritable bowel syndrome (IBS), promoting gut health
Read more in plain English ↓Plain-language summary for general understanding - not medical advice. Always follow your pharmacist/doctor.
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Source: Pharmacy and Poisons Board · fetched 2026-01-28 22:04:24 · updated 2026-03-23 04:49:33
About this medicine
Saccharomyces is a type of yeast used as a dietary supplement to support digestive health.
What it treats
- digestive issues
- diarrhea
- irritable bowel syndrome (IBS)
- promoting gut health
How it works
Saccharomyces helps balance good bacteria in the gut, which can improve digestion and overall gut health.
Who it's for
Adults and children experiencing digestive problems or those looking to support their gut health.
AI-assisted summary grounded in BNF data - general information only, not medical advice. Always confirm with your pharmacist or doctor.
Clinical monograph: saccharomyces
Saccharomyces, commonly known as brewer's or baker's yeast, is a genus of fungi used for its fermentative properties. It is primarily utilized in the production of alcoholic beverages, baking, and as a dietary supplement due to its probiotic effects. Saccharomyces boulardii, a specific strain, is recognized for its beneficial effects on gastrointestinal health.
Indications
- Antibiotic-associated diarrhea
- Acute infectious diarrhea
- Chronic diarrhea in conditions like irritable bowel syndrome
- Maintenance of gut flora during antibiotic therapy
- Prevention of traveler's diarrhea
Dosage
Children: Refer to specific product guidelines for paediatric dosages, as they may vary depending on the formulation and age of the child.
Adults: Refer to specific product guidelines for recommended adult dosages, as they may vary depending on the formulation.
Mechanism of action
Saccharomyces boulardii exerts its effects by promoting gut health through various mechanisms. It enhances the intestinal barrier function, modulates local immune responses, and inhibits the growth of pathogenic bacteria. It also produces short-chain fatty acids and aids in the maintenance of gut microbiota balance, which can help in reducing diarrhea and improving gut health.
Pharmacodynamics
The pharmacodynamics of Saccharomyces involve its ability to adhere to intestinal mucosa, which helps in restoring the normal flora of the gut. It has been shown to reduce the duration and severity of diarrhea, particularly in cases of antibiotic-associated diarrhea and infectious diarrhea. Additionally, it may enhance the absorption of nutrients and support the immune system.
Pharmacokinetics
Saccharomyces boulardii is generally not absorbed systemically; instead, it acts locally in the gastrointestinal tract. It survives passage through the stomach and colonizes the intestines, where it exerts its beneficial effects. The viability of Saccharomyces is influenced by factors such as pH, temperature, and the presence of other gastrointestinal microorganisms. Its effects are typically observed within a few days of administration.
Adverse effects
- Gastrointestinal upset
- Bloating
- Gas
- Diarrhea
Interactions
- May interact with antifungal medications
- Potential interactions with immunosuppressive drugs
Precautions
- Caution in patients with compromised immune systems
- Use with caution in patients with a history of yeast allergies
Pregnancy
Limited data available, consult healthcare provider before use.
Breast-feeding
Generally considered safe, but consult healthcare provider.
Storage
Store in a cool, dry place, away from direct sunlight.
Formulations
- Capsules
- Tablets
- Powder for oral suspension
- Granules
AI-synthesized from BNF references - general information only, not a substitute for professional medical advice or the current BNF. Verify doses with a pharmacist.
This drug in other countries
The same active ingredient registered across other registries we cover - including different brands.