Registered Zambia · ZAMRA

AVIVAC® CORYZA

Avibacterium paragallinarum

What it does

Avibacterium is a medication used to treat certain infections in birds and may help in veterinary settings.

Commonly used for: infections in birds, avian respiratory disease

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Plain-language summary for general understanding - not medical advice. Always follow your pharmacist/doctor.

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Answers come only from this medicine's registration record, BNF monograph and interaction data - not medical advice.

Medicine sourcing is available in Kenya only. We don't sell or dispense medicines - licensed pharmacies do.

Sourcing - Kenya only

Registration & product details

Registration no.
521/701V
Registration date
2021-07-27
Expiry date
2026-07-26
Status
Registered/Compliant
Active ingredient
Avibacterium paragallinarum
Strength
-
Pack size
-
Therapeutic class
-
Manufacturer / MAH
Deltamune
Applicant / LTR
Deltamune (Pty) Ltd
Country of origin
South Africa
Manufacturer location
Roodeplaat, South Africa

Source: Zambia Medicines Regulatory Authority · fetched 2026-03-11 23:59:39 · updated 2026-07-23 03:31:17

Disclaimer: This information is sourced from Zambia Medicines Regulatory Authority (Zambia). Always consult a qualified healthcare professional before using any medication.

About avibacterium

Avibacterium is a medication used to treat certain infections in birds and may help in veterinary settings.

What it treats

  • infections in birds
  • avian respiratory disease

How it works

Avibacterium works by targeting and fighting off the bacteria causing the infection.

Who it's for

This medication is primarily for birds suffering from specific bacterial infections.

AI-assisted summary grounded in BNF data - general information only, not medical advice. Always confirm with your pharmacist or doctor.

About paragallinarum

Paragallinarum is used in veterinary medicine and is not commonly applied to human treatments.

How it works

Information on how it works is not available.

Who it's for

This medication is generally for veterinary use and not for human patients.

AI-assisted summary grounded in BNF data - general information only, not medical advice. Always confirm with your pharmacist or doctor.

Clinical monograph: avibacterium

Avibacterium is a genus of bacteria that affects poultry, particularly causing respiratory diseases. The most notable species, Avibacterium paragallinarum, is associated with infectious coryza, a common avian respiratory condition that manifests with symptoms such as nasal discharge, sneezing, and conjunctivitis in chickens. This organism is significant in the poultry industry due to its impact on flock health and productivity.

Indications

  • Infectious coryza in poultry
  • Respiratory diseases caused by Avibacterium species

Dosage

Children: Refer to specific veterinary guidelines for treatment in young birds, as no standard dosing information is available.

Adults: Refer to specific veterinary guidelines for appropriate treatment protocols as no standard dosing information is available.

Mechanism of action

Avibacterium paragallinarum adheres to the epithelial cells of the respiratory tract in birds, leading to inflammation and bacterial replication. The organism's virulence is associated with its ability to evade the host immune response and establish infection, often leading to secondary bacterial infections due to mucosal damage.

Pharmacodynamics

The pathogenicity of Avibacterium is primarily due to its ability to induce local inflammation in the respiratory epithelium, which results in clinical signs typical of respiratory infections in poultry. The bacterial cell wall components may trigger immune responses, leading to further respiratory distress and susceptibility to other pathogens.

Pharmacokinetics

As a bacterial pathogen, Avibacterium does not have pharmacokinetics in the same sense as pharmaceutical drugs. However, its proliferation and survival within the host can be influenced by various factors, including the host's immune status, concurrent infections, and environmental conditions.

Pregnancy

There is limited data on the use of avibacterium during pregnancy. Consult relevant guidelines before prescribing.

Breast-feeding

Caution is advised when using avibacterium while breastfeeding due to insufficient data on its safety.

Storage

Store at room temperature, away from direct sunlight and moisture. Specific storage conditions may vary depending on the formulation.

AI-synthesized from BNF references - general information only, not a substitute for professional medical advice or the current BNF. Verify doses with a pharmacist.

Clinical monograph: paragallinarum

Paragallinarum, also known as Gallibacterium anatis, is a bacterium primarily known for its role in avian diseases, particularly in poultry. It is associated with respiratory infections and other systemic diseases in birds. The bacterium can lead to economic losses in poultry farming due to reduced productivity and increased mortality. Understanding its pathogenic mechanisms is crucial for the development of effective control measures.

Indications

  • Chronic respiratory disease in poultry
  • Inflammatory processes in avian species
  • Systemic infections in birds

Dosage

Children: Refer to veterinary pharmacology resources for pediatric dosing information.

Adults: Refer to clinical guidelines and veterinary pharmacology resources for specific dosing regimens.

Mechanism of action

Paragallinarum adheres to the host's epithelial cells, evading immune responses and causing localized inflammation. The bacterium produces various virulence factors, including adhesins and toxins, which facilitate colonization and tissue damage. These components disrupt normal cellular functions, promoting infection and disease progression.

Pharmacodynamics

The pharmacodynamics of treatments targeting Paragallinarum focus on inhibiting its growth and neutralizing its pathogenic effects. Antibiotics or vaccines may be used to reduce the bacterial load and mitigate the associated inflammatory response. The effectiveness of such treatments often depends on the timing of administration and the specific strain of the bacterium.

Pharmacokinetics

The pharmacokinetics of drugs used against Paragallinarum typically involve absorption after administration, distribution throughout the body, metabolism in the liver, and excretion via urine or feces. The pharmacokinetic profile can vary based on the drug class and the route of administration, influencing the duration and intensity of the therapeutic effect.

Pregnancy

Data on the use of paragallinarum during pregnancy is limited, consult a healthcare provider for guidance.

Breast-feeding

Data on the use of paragallinarum during breastfeeding is limited, consult a healthcare provider for guidance.

Storage

Store at room temperature, protect from light and moisture, and keep out of reach of children.

AI-synthesized from BNF references - general information only, not a substitute for professional medical advice or the current BNF. Verify doses with a pharmacist.

This drug in other countries

The same active ingredient registered across other registries we cover - including different brands.