What it does
Cromoglycic is a medication used to prevent allergic reactions and asthma symptoms.
Commonly used for: asthma, allergic rhinitis (hay fever)
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Source: Pharmacy and Poisons Board · fetched 2026-01-28 22:00:31 · updated 2026-03-23 04:45:45
About this medicine
Cromoglycic is a medication used to prevent allergic reactions and asthma symptoms.
What it treats
- asthma
- allergic rhinitis (hay fever)
How it works
Cromoglycic helps to block allergens and prevent the release of substances that cause inflammation in the airways.
Who it's for
This medicine is for individuals who suffer from asthma or allergies.
AI-assisted summary grounded in BNF data - general information only, not medical advice. Always confirm with your pharmacist or doctor.
Clinical monograph: cromoglycic
Cromoglycic acid, also known as sodium cromoglycate, is a medication primarily used as a mast cell stabilizer. It is indicated for the prevention and treatment of asthma, allergic rhinitis, and conjunctivitis. By inhibiting the release of inflammatory mediators from mast cells, it helps to prevent allergic reactions and asthma exacerbations.
Indications
- Asthma
- Allergic rhinitis
- Allergic conjunctivitis
- Exercise-induced bronchospasm
Dosage
Children: Refer to the BNF for Children for specific dosing information.
Adults: Refer to the BNF for specific dosing guidelines.
Mechanism of action
Cromoglycic acid acts by stabilizing the membranes of mast cells, thereby inhibiting their degranulation and the subsequent release of histamine and other pro-inflammatory mediators. This action reduces the inflammatory response associated with allergic reactions and asthma.
Pharmacodynamics
Cromoglycic acid has anti-inflammatory properties, particularly in the respiratory tract. It reduces the hyperresponsiveness of airways to allergens and irritants, leading to a decrease in symptoms of asthma and other allergic conditions. Its effectiveness is primarily preventative, as it does not relieve acute asthma attacks.
Pharmacokinetics
Cromoglycic acid is poorly absorbed from the gastrointestinal tract, leading to low systemic bioavailability. It is primarily excreted unchanged in the urine. The onset of action is slow, with peak effects occurring after several days of consistent use. The drug has a short half-life, necessitating multiple daily dosing for optimal effect.
Adverse effects
- local irritation
- cough
- dry throat
- headache
- nausea
Precautions
- Use with caution in patients with a history of asthma or other chronic respiratory conditions.
- Monitor for potential allergic reactions.
Pregnancy
Cromoglycic acid is classified as a category B drug. Animal studies have not shown harm to the fetus, but there are no adequate and well-controlled studies in pregnant women.
Breast-feeding
Cromoglycic acid is excreted in breast milk, but effects on nursing infants are not well studied. Use with caution.
Storage
Store at room temperature, away from direct light and moisture. Keep out of reach of children.
Formulations
- Inhalation solution
- Nasal spray
- Ophthalmic solution
AI-synthesized from BNF references - general information only, not a substitute for professional medical advice or the current BNF. Verify doses with a pharmacist.