OXOFERIN SOLUTION (Each 100ml contains tetrachlorodecaoxide 136.9 by 106 pmd)
tetrachlorodecaoxide
What it does
Tetrachlorodecaoxide is a chemical compound that may be used in specific medical applications.
Read more in plain English ↓Plain-language summary for general understanding - not medical advice. Always follow your pharmacist/doctor.
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Sourcing - Kenya onlyRegistration & product details
Source: Food and Drugs Authority · fetched 2026-05-08 08:00:49 · updated 2026-10-20 04:00:13
About this medicine
Tetrachlorodecaoxide is a chemical compound that may be used in specific medical applications.
How it works
The exact way tetrachlorodecaoxide works in the body isn't fully understood.
Who it's for
This medication is typically used under special circumstances as advised by a healthcare professional.
AI-assisted summary grounded in BNF data - general information only, not medical advice. Always confirm with your pharmacist or doctor.
Clinical monograph: tetrachlorodecaoxide
BNF-referencedTetrachlorodecaoxide (TCDO) is a synthetic compound, specifically formulated as WF 10, which is a 1:10 dilution intended for intravenous administration. It was developed as an adjunctive therapy for patients with AIDS, especially those on combination antiretroviral therapy and those requiring prophylaxis against opportunistic infections. The drug is designed to target macrophages, thereby influencing immune responses and modulating inflammatory reactions.
Indications
- AIDS
- Opportunistic infection prophylaxis
- Adjunctive therapy in combination with antiretroviral regimens
Dosage
Children: Refer to BNF for Children for specific dosing in paediatrics.
Adults: Refer to BNF for specific dosing in adults.
Mechanism of action
Tetrachlorodecaoxide acts primarily by targeting macrophages, which are crucial components of the immune system. It modulates immune responses by downregulating inappropriate inflammatory reactions, both in vitro and in vivo. This modulation may aid in improving the immune status of patients suffering from diseases such as AIDS.
Pharmacodynamics
The pharmacodynamics of TCDO involve its interaction with immune cells, particularly macrophages, leading to a modulation of the immune response. By downregulating inflammatory mediators, TCDO may help in reducing excessive immune activation and inflammation, which is often observed in patients with AIDS and during opportunistic infections.
Pharmacokinetics
The pharmacokinetics of tetrachlorodecaoxide are not well documented in the literature. General principles of pharmacokinetics suggest that intravenous administration allows for rapid distribution in the body. However, specific data regarding absorption, distribution, metabolism, and excretion are limited and should be referred to in clinical guidelines and literature.
Pregnancy
There is limited data on the use of tetrachlorodecaoxide during pregnancy. Consult relevant guidelines and consider the potential risks versus benefits.
Breast-feeding
Limited data available on the excretion of tetrachlorodecaoxide in human milk. Exercise caution and consider the potential risks versus benefits.
Storage
Store at room temperature, away from direct sunlight and moisture. Keep out of reach of children.
Formulations
- WF 10 (1:10 dilution of tetrachlorodecaoxide for intravenous injection)
AI-synthesized from BNF references - general information only, not a substitute for professional medical advice or the current BNF. Verify doses with a pharmacist.
Molecular reference: tetrachlorodecaoxide
PubChem CID 3000391Molecular formula: Cl4H2O11-4
Mechanism of action
WF 10 is a 1: 10 dilution of tetrachlorodecaoxide (TCDO) formulated for intravenous injection. It was developed by Oxo Chemie in Switzerland as an adjunctive therapy to combination antiretroviral and opportunistic infection prophylaxis regimens in AIDS patients. WF 10 specifically targets macrophages. WF10 potentially modulates disease-related up-regulation of immune responses both in vitro and in vivo. Thus immune response is influenced in a way that inappropriate inflammatory reactions are downregulated.
Source: PubChem (NCBI) · pathways from PathBank, Reactome, WikiPathways & PharmGKB.
This drug in other countries
The same active ingredient registered across other registries we cover - including different brands.