Valid Ghana · FDA Ghana

PROSTENAL NIGHT TABLETS (Each film-coated tablet Saw palmetto Ext/ Cranberry/ Ashwagandha/ Vit B1/ Vit B2/ Zinc/ Vit D3 320mg/ 250mg/ 50mg/0.55mg/0.7mg/10mg/10mcg)

Saw palmetto Ext/ Cranberry/ Ashwagandha/ Vit B1/ Vit B2/ Zinc/ Vit D3

FDA/SD.255-091752 Saw palmetto Ext/ Cranberry/ Ashwagandha/ Vit B1/ Vit B2/ Zinc/ Vit D3 320mg/ 250mg/ 50mg/0.55mg/0.7mg/10mg/10mcg

What it does

Ashwagandha is a natural herb often used to help the body manage stress and improve overall well-being.

Commonly used for: stress relief, anxiety management, improving mood, supporting energy levels

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Plain-language summary for general understanding - not medical advice. Always follow your pharmacist/doctor.

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Registration & product details

Registration no.
FDA/SD.255-091752
Registration date
2025-11-25
Expiry date
2030-10-01
Status
Valid
Active ingredient
Saw palmetto Ext/ Cranberry/ Ashwagandha/ Vit B1/ Vit B2/ Zinc/ Vit D3
Strength
320mg/ 250mg/ 50mg/0.55mg/0.7mg/10mg/10mcg
Pack size
-
Therapeutic class
-
RxNorm RxCUI
125933
Manufacturer / MAH
Walmark
Country of origin
Czech Republic
Manufacturer location
Polní 836, 739 61 Třinec-Třinec 1, Czechia

Source: Food and Drugs Authority · fetched 2026-04-18 08:33:07 · updated 2026-10-30 04:00:03

Disclaimer: This information is sourced from Food and Drugs Authority (Ghana). Always consult a qualified healthcare professional before using any medication.

About ashwagandha

Ashwagandha is a natural herb often used to help the body manage stress and improve overall well-being.

What it treats

  • stress relief
  • anxiety management
  • improving mood
  • supporting energy levels

How it works

Ashwagandha is thought to help balance hormones and reduce stress by calming the nervous system.

Who it's for

It is suitable for adults looking for natural support in managing stress and enhancing mental clarity.

AI-assisted summary grounded in BNF data - general information only, not medical advice. Always confirm with your pharmacist or doctor.

About cranberry

Cranberry is a natural product often used to support urinary health.

What it treats

  • urinary tract infections (UTIs)
  • bladder infections

How it works

Cranberry may help prevent bacteria from sticking to the urinary tract, reducing the risk of infections.

Who it's for

Cranberry is suitable for adults and children who want to support their urinary health.

AI-assisted summary grounded in BNF data - general information only, not medical advice. Always confirm with your pharmacist or doctor.

About ext

Ext is a medication used to treat various conditions by affecting how your body functions.

What it treats

  • specific medical conditions as determined by a healthcare provider

How it works

Ext works by influencing certain processes in the body to help manage symptoms or treat conditions.

Who it's for

Ext is prescribed for individuals based on their specific health needs.

AI-assisted summary grounded in BNF data - general information only, not medical advice. Always confirm with your pharmacist or doctor.

About palmetto

Palmetto is a natural supplement often used for health issues related to the prostate.

What it treats

  • benign prostatic hyperplasia (BPH)
  • prostate health

How it works

Palmetto is believed to support prostate health by reducing symptoms associated with an enlarged prostate.

Who it's for

Palmetto is typically used by men, especially older adults, who are experiencing urinary symptoms due to prostate issues.

AI-assisted summary grounded in BNF data - general information only, not medical advice. Always confirm with your pharmacist or doctor.

About saw

Saw is a herbal supplement often used for various health purposes.

What it treats

  • benign prostatic hyperplasia (BPH)
  • hair loss
  • prostate health

How it works

Saw is believed to work by affecting hormone levels and reducing inflammation.

Who it's for

Adults looking for support with prostate health or hair loss.

Cautions

  • • Consult a healthcare professional before use, especially if you are pregnant, breastfeeding, or have other medical conditions.

AI-assisted summary grounded in BNF data - general information only, not medical advice. Always confirm with your pharmacist or doctor.

About vit

Vitamin supplements are used to provide essential nutrients that may be missing from your diet.

What it treats

  • vitamin deficiency
  • poor diet
  • boosting overall health

How it works

Vitamins help your body function properly and support overall health by aiding in various biological processes.

Who it's for

People who may not get enough vitamins from their food, including those with dietary restrictions, certain health conditions, or increased nutrient needs.

Cautions

  • • Consult a healthcare professional before starting any vitamin supplement, especially if you are pregnant, breastfeeding, or have underlying health conditions.

AI-assisted summary grounded in BNF data - general information only, not medical advice. Always confirm with your pharmacist or doctor.

Clinical monograph: ashwagandha

Ashwagandha, also known as Withania somnifera, is an adaptogenic herb commonly used in traditional Ayurvedic medicine. It is renowned for its potential to enhance the body's resilience to stress, improve energy levels, and support overall health. Ashwagandha is frequently used to manage conditions such as anxiety, insomnia, and fatigue, and is also noted for its potential neuroprotective and anti-inflammatory properties.

Indications

  • Anxiety disorders
  • Stress management
  • Insomnia
  • Fatigue
  • Cognitive enhancement
  • Neuroprotection
  • Anti-inflammatory conditions

Dosage

Children: Refer to established guidelines, as specific pediatric dosing information is not universally defined.

Adults: Refer to established guidelines and individual product recommendations, as specific dosing can vary based on the formulation and concentration of ashwagandha.

Mechanism of action

Ashwagandha is believed to exert its effects through several mechanisms. It modulates the hypothalamic-pituitary-adrenal (HPA) axis, thereby reducing cortisol levels and alleviating stress. The herb also possesses antioxidant properties, which may protect against oxidative stress. Additionally, ashwagandha is thought to influence neurotransmitter systems, enhancing GABAergic activity, which may contribute to its anxiolytic effects.

Pharmacodynamics

Ashwagandha has been shown to have a wide range of pharmacological effects, including anxiolytic, adaptogenic, anti-inflammatory, and neuroprotective actions. Its active constituents, such as withanolides, are believed to mediate these effects by interacting with various biological pathways, including those involved in stress response and inflammation. The herb's adaptogenic properties help the body to maintain homeostasis during stress, potentially leading to improved mental and physical performance.

Pharmacokinetics

The pharmacokinetics of ashwagandha are not thoroughly characterized, but studies suggest that its active compounds are absorbed through the gastrointestinal tract. The bioavailability of withanolides appears to be influenced by the preparation and formulation of the extract. Metabolism primarily occurs in the liver, and elimination may involve both renal and biliary pathways. The onset of action can vary, with some effects observed within days to weeks of consistent use.

Adverse effects

  • Gastrointestinal upset
  • Diarrhea
  • Nausea
  • Vomiting
  • Headache
  • Drowsiness
  • Allergic reactions

Interactions

  • May potentiate the effects of sedatives
  • May interact with thyroid hormone medications
  • May alter blood sugar levels, affecting antidiabetic medications

Precautions

  • Use with caution in individuals with autoimmune diseases
  • Monitor blood sugar levels in diabetic patients
  • Caution in individuals with hormone-sensitive conditions

Pregnancy

Generally not recommended due to insufficient evidence of safety.

Breast-feeding

Limited information available, consult healthcare provider.

Storage

Store in a cool, dry place, away from direct sunlight.

Formulations

  • Powdered root
  • Capsules
  • Extracts
  • Teas

AI-synthesized from BNF references - general information only, not a substitute for professional medical advice or the current BNF. Verify doses with a pharmacist.

Clinical monograph: cranberry

Cranberry, primarily derived from the Vaccinium macrocarpon plant, is commonly used for its potential role in preventing urinary tract infections (UTIs). It contains various bioactive compounds, including proanthocyanidins, which are believed to inhibit the adhesion of certain bacteria, particularly Escherichia coli, to the urinary tract walls. Cranberry is available in various forms, including juice, capsules, and tablets.

Indications

  • Prevention of urinary tract infections
  • Supportive treatment for urinary tract health

Dosage

Children: Refer to product guidelines and consult healthcare professionals for appropriate dosing in children.

Adults: Refer to specific product guidelines, as dosing can vary based on formulation and concentration.

Mechanism of action

Cranberry's primary mechanism of action involves the presence of proanthocyanidins, which prevent the adherence of uropathogenic E. coli to the uroepithelial cells. This reduces the ability of the bacteria to colonize and cause infection. Additionally, cranberry may have antioxidant properties, contributing to its overall health benefits.

Pharmacodynamics

Cranberry demonstrates antibacterial activity specifically against uropathogenic strains of bacteria. The proanthocyanidins in cranberry have been shown to alter the properties of bacterial fimbriae, thereby interfering with their ability to adhere to the bladder wall. This action helps reduce the incidence of urinary tract infections. Furthermore, cranberry may exert a mild diuretic effect, promoting increased urine flow.

Pharmacokinetics

Cranberry components, particularly its polyphenols, undergo extensive metabolism in the gastrointestinal tract. After ingestion, they are absorbed and metabolized in the liver, where they can be excreted in the urine. Peak plasma concentrations of cranberry constituents occur within 1 to 2 hours post-ingestion. Elimination half-lives vary depending on the specific compound and individual metabolism.

Adverse effects

  • Gastrointestinal upset
  • Diarrhea
  • Nausea
  • Allergic reactions

Interactions

  • May interact with warfarin, potentially increasing bleeding risk
  • May alter the effectiveness of certain medications metabolized by the liver

Precautions

  • Use with caution in patients with a history of kidney stones
  • Monitor for potential interactions with anticoagulants

Pregnancy

Cranberry is generally regarded as safe during pregnancy when consumed in food amounts. However, consult a healthcare provider for supplementation.

Breast-feeding

Cranberry is likely safe during breastfeeding when consumed as food. Consult a healthcare provider for higher doses.

Storage

Store in a cool, dry place away from direct sunlight. Refrigerate after opening if in juice form.

Formulations

  • Dried cranberries
  • Cranberry juice
  • Cranberry extract capsules
  • Cranberry tablets

AI-synthesized from BNF references - general information only, not a substitute for professional medical advice or the current BNF. Verify doses with a pharmacist.

Clinical monograph: palmetto

Palmetto, commonly known as saw palmetto, is derived from the fruit of the Serenoa repens plant. It is often used as a herbal supplement, primarily for its potential benefits in managing benign prostatic hyperplasia (BPH) and other urinary tract symptoms in men. In addition to its urological applications, saw palmetto may have roles in hormone regulation and potentially in hair loss treatments.

Indications

  • Benign prostatic hyperplasia (BPH)
  • Urinary tract symptoms related to prostate enlargement
  • Potentially for androgenic alopecia (hair loss)

Dosage

Children: Not established; use in children should be approached cautiously and under medical supervision.

Adults: Refer to specific product guidelines as dosing can vary widely depending on formulation and concentration.

Mechanism of action

Saw palmetto is believed to work by inhibiting the conversion of testosterone to dihydrotestosterone (DHT) via the action of 5-alpha reductase. This inhibition may reduce the size of the prostate and alleviate associated symptoms. Additionally, it may exert anti-inflammatory effects, which could further benefit urinary tract health.

Pharmacodynamics

The pharmacodynamic effects of saw palmetto include the modulation of androgenic activity and a reduction in prostatic cell proliferation. It may also have a mild diuretic effect, promoting urine flow. Saw palmetto can affect hormone levels, potentially impacting testosterone and estrogen metabolism.

Pharmacokinetics

Palmetto is typically administered orally, and its bioavailability can be influenced by factors such as formulation and meal composition. The active compounds are thought to be absorbed in the gastrointestinal tract. Saw palmetto is metabolized by the liver and excreted primarily through the urine, although specific pharmacokinetic parameters such as half-life and clearance rates are not well-established.

Adverse effects

  • Gastrointestinal disturbances
  • Headache
  • Dizziness
  • Allergic reactions
  • Sexual dysfunction

Interactions

  • May interact with anticoagulants, increasing the risk of bleeding
  • Can potentially affect the metabolism of drugs processed by the liver

Precautions

  • Use with caution in patients with hormone-sensitive conditions
  • Monitor for side effects in patients on concurrent medications

Pregnancy

Safety during pregnancy has not been established; use is generally not recommended.

Breast-feeding

Not enough is known about the safety of palmetto during breastfeeding; caution is advised.

Storage

Store in a cool, dry place away from light, and keep out of reach of children.

Formulations

  • Capsules
  • Tablets
  • Liquid extracts

AI-synthesized from BNF references - general information only, not a substitute for professional medical advice or the current BNF. Verify doses with a pharmacist.

This drug in other countries

The same active ingredient registered across other registries we cover - including different brands.