ZINCOVIT SYRUP
VIT A/COLECALAFEOL MULTIVITAMINS AND MINERALS
What it does
Colecalafeol is a supplement that helps maintain healthy levels of vitamin D in the body.
Commonly used for: Vitamin D deficiency, Bone health, Support for immune function
Read more in plain English ↓Plain-language summary for general understanding - not medical advice. Always follow your pharmacist/doctor.
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Medicine sourcing is available in Kenya only. We don't sell or dispense medicines - licensed pharmacies do.
Sourcing - Kenya onlyRegistration & product details
Source: Food and Drugs Authority · fetched 2026-04-18 08:37:11 · updated 2026-09-29 04:00:10
About colecalafeol
Colecalafeol is a supplement that helps maintain healthy levels of vitamin D in the body.
What it treats
- Vitamin D deficiency
- Bone health
- Support for immune function
How it works
Colecalafeol provides vitamin D, which is essential for calcium absorption and maintaining strong bones.
Who it's for
It is suitable for individuals who need extra vitamin D, such as those with limited sun exposure or certain health conditions.
AI-assisted summary grounded in BNF data - general information only, not medical advice. Always confirm with your pharmacist or doctor.
About minerals
Minerals are essential nutrients that help your body function properly. They play a key role in various bodily processes, including bone health, hydration, and maintaining overall well-being.
What it treats
- supports overall health
- maintains bone strength
- aids in hydration
- helps in muscle function
How it works
Minerals work by contributing to various physiological functions in the body, such as building strong bones, transmitting nerve signals, and regulating fluid balance.
Who it's for
Minerals are important for everyone, especially those with dietary deficiencies, athletes, and individuals with specific health conditions.
AI-assisted summary grounded in BNF data - general information only, not medical advice. Always confirm with your pharmacist or doctor.
About multivitamins
Multivitamins are dietary supplements that provide a combination of vitamins and minerals to support overall health.
What it treats
- general health maintenance
- nutritional deficiencies
- support during pregnancy
How it works
They help fill nutritional gaps in the diet, ensuring the body gets essential vitamins and minerals needed for various bodily functions.
Who it's for
Multivitamins are suitable for people of all ages, including those with specific dietary restrictions or increased nutritional needs.
AI-assisted summary grounded in BNF data - general information only, not medical advice. Always confirm with your pharmacist or doctor.
About vit
Vitamin supplements are used to provide essential nutrients that may be missing from your diet.
What it treats
- vitamin deficiency
- poor diet
- boosting overall health
How it works
Vitamins help your body function properly and support overall health by aiding in various biological processes.
Who it's for
People who may not get enough vitamins from their food, including those with dietary restrictions, certain health conditions, or increased nutrient needs.
Cautions
- • Consult a healthcare professional before starting any vitamin supplement, especially if you are pregnant, breastfeeding, or have underlying health conditions.
AI-assisted summary grounded in BNF data - general information only, not medical advice. Always confirm with your pharmacist or doctor.
Clinical monograph: colecalafeol
Colecalafeol, commonly known as Vitamin D3, is a fat-soluble vitamin that plays a crucial role in calcium and phosphorus metabolism in the body. It is synthesized in the skin in response to sunlight exposure and can also be obtained from dietary sources. Adequate levels of colecalafeol are essential for maintaining healthy bones and teeth, supporting immune function, and modulating cell growth.
Indications
- Vitamin D deficiency
- Osteoporosis prevention and treatment
- Rickets in children
- Osteomalacia in adults
- Hypoparathyroidism
Dosage
Children: Refer to local guidelines for specific dosing recommendations based on individual needs and clinical conditions.
Adults: Refer to local guidelines for specific dosing recommendations based on individual needs and clinical conditions.
Mechanism of action
Colecalafeol is converted in the liver to calcidiol and subsequently in the kidneys to calcitriol, the active form of Vitamin D. Calcitriol binds to Vitamin D receptors in various tissues, leading to increased intestinal absorption of calcium and phosphate, enhanced renal tubular reabsorption of calcium, and mobilization of calcium from the bone, thus contributing to the maintenance of serum calcium levels.
Pharmacodynamics
Colecalafeol influences calcium and phosphate homeostasis, promoting bone health and mineralization. It has also been implicated in immune system modulation and may affect the risk of certain chronic diseases. Deficiency in colecalafeol can lead to rickets in children and osteomalacia in adults, conditions characterized by weakened bones.
Pharmacokinetics
Colecalafeol is absorbed in the intestines and its bioavailability is enhanced when taken with fats. It is stored in adipose tissue and has a half-life of several weeks. The primary metabolic pathway involves conversion to calcidiol in the liver and then to calcitriol in the kidneys. The renal conversion is tightly regulated by parathyroid hormone and serum calcium levels.
Adverse effects
- Hypercalcemia
- Nausea
- Vomiting
- Constipation
- Abdominal pain
- Weakness
- Fatigue
- Headache
- Dizziness
Interactions
- Thiazide diuretics (increased risk of hypercalcemia)
- Digoxin (risk of digoxin toxicity due to hypocalcemia)
- Anticonvulsants (may reduce vitamin D metabolism)
- Mineral oil (may impair absorption of vitamin D)
Precautions
- Monitor calcium levels during therapy
- Use with caution in patients with renal impairment
- Assess for signs of vitamin D toxicity
- Consider dietary calcium intake
Pregnancy
Colecalciferol is generally considered safe during pregnancy when used at recommended doses. It is important to consult a healthcare provider for appropriate supplementation.
Breast-feeding
Colecalciferol is excreted in breast milk. It is usually considered safe for nursing mothers, but it is advisable to consult a healthcare provider regarding supplementation.
Storage
Store in a cool, dry place away from direct sunlight. Keep out of reach of children.
Formulations
- Soft capsules
- Tablets
- Oral solution
- Powder for reconstitution
AI-synthesized from BNF references - general information only, not a substitute for professional medical advice or the current BNF. Verify doses with a pharmacist.
Clinical monograph: minerals
Minerals are essential inorganic nutrients that play crucial roles in various physiological processes within the human body. They are required for numerous biochemical functions, including enzyme activation, hormone production, and maintaining structural integrity of bones and teeth. Common minerals include calcium, potassium, magnesium, sodium, and iron, among others, each serving specific functions in health and disease management.
Indications
- Calcium deficiency
- Iron deficiency anemia
- Magnesium deficiency
- Potassium depletion
- Electrolyte imbalances
Dosage
Children: Paediatric doses of minerals should be determined based on age, weight, and specific clinical indications. Consultation with pediatric dosing guidelines or the BNF for Children is recommended.
Adults: Doses of minerals vary widely based on the specific mineral and the condition being treated. It is essential to refer to established guidelines or the relevant pharmacopoeia for specific dosing recommendations.
Mechanism of action
Minerals exert their effects through various mechanisms, often by interacting with specific enzymes or cellular receptors. For example, calcium is vital for muscle contraction and neurotransmitter release, while iron is a key component of hemoglobin, facilitating oxygen transport in the blood. Additionally, minerals can influence physiological pathways such as nerve conduction, fluid balance, and cellular signaling.
Pharmacodynamics
Minerals contribute to numerous physiological functions, including muscle contraction, nerve impulse transmission, and cellular metabolism. Their pharmacodynamic effects depend on the specific mineral. For instance, magnesium plays a role in over 300 enzymatic reactions, while potassium is crucial for maintaining normal cellular function and fluid balance. Imbalances can lead to conditions such as hypertension, osteoporosis, and anemia.
Pharmacokinetics
The absorption, distribution, metabolism, and excretion of minerals vary widely among different types. Generally, minerals are absorbed in the gastrointestinal tract, with bioavailability influenced by dietary factors and the presence of other nutrients. For example, vitamin C enhances iron absorption, while phytates and oxalates can inhibit it. Once absorbed, minerals are distributed in the body fluids and tissues, with excess amounts typically excreted through the kidneys. Specific transport proteins may facilitate their uptake and distribution.
Pregnancy
Minerals are essential nutrients during pregnancy, with some, like iron and calcium, being particularly important. However, excessive intake of certain minerals can be harmful.
Breast-feeding
Minerals are important for lactating women, as they are necessary for both maternal health and the development of the nursing infant. Adequate mineral intake is recommended, but supplementation should be approached cautiously.
Storage
Store in a cool, dry place away from direct sunlight. Specific storage conditions may vary based on the type of mineral supplement.
AI-synthesized from BNF references - general information only, not a substitute for professional medical advice or the current BNF. Verify doses with a pharmacist.
Clinical monograph: multivitamins
Multivitamins are dietary supplements containing a combination of vitamins, and often minerals, intended to provide nutrients that may be lacking in an individual's diet. They are commonly used to prevent or treat vitamin deficiencies due to poor diet, certain health conditions, or increased physiological needs. Multivitamins can contribute to overall health and well-being when taken as part of a balanced diet.
Indications
- Vitamin deficiency prevention
- Nutritional supplementation
- Support during pregnancy
- Support in elderly patients
- Immune system support
- General health and well-being
Dosage
Children: Refer to the BNF for Children for appropriate pediatric dosing, as this can vary based on age, dietary needs, and specific formulations of multivitamins.
Adults: Refer to specific product guidelines for dosing, as multivitamin formulations can vary widely. Generally, a typical adult multivitamin may be taken once daily, but this can depend on the specific formulation and the individual's nutritional needs.
Mechanism of action
Multivitamins provide essential vitamins and minerals that play critical roles in various biochemical processes in the body. For instance, B vitamins are involved in energy metabolism, vitamin C acts as an antioxidant, and vitamin D supports calcium absorption for bone health. The specific mechanism of action varies with each vitamin and mineral, as they contribute to enzymatic reactions, hormone production, and cellular functions.
Pharmacodynamics
The pharmacodynamics of multivitamins involves the physiological effects that these vitamins and minerals have on the body. Each vitamin and mineral has a unique role, such as supporting immune function, promoting growth and development, and mitigating oxidative stress. Adequate levels of these nutrients are essential for maintaining homeostasis and preventing deficiency-related diseases.
Pharmacokinetics
The pharmacokinetics of multivitamins can vary widely depending on the specific vitamins and minerals included. Water-soluble vitamins, such as B-complex and vitamin C, are typically absorbed in the intestines and excreted in urine when in excess. Fat-soluble vitamins, such as vitamins A, D, E, and K, are absorbed along with dietary fats and stored in body tissues, which can lead to toxicity if taken in excessive amounts. The bioavailability of these nutrients can be influenced by dietary factors, the presence of other nutrients, and individual metabolism.
Adverse effects
- Nausea
- Vomiting
- Diarrhea
- Constipation
- Allergic reactions
- Headache
Interactions
- Anticoagulants may have altered effects due to vitamin K
- Certain antibiotics may have reduced efficacy due to iron or calcium in multivitamins
- Absorption of some medications may be affected by the presence of fat-soluble vitamins
Precautions
- Use with caution in patients with renal impairment
- Monitor for potential overdose, particularly in children
- Consult a healthcare provider before use in patients with underlying health conditions
Pregnancy
Generally considered safe, but high doses of certain vitamins should be avoided. Consult a healthcare provider.
Breast-feeding
Usually safe, but high doses of certain vitamins should be avoided. Consult a healthcare provider.
Storage
Store in a cool, dry place away from direct sunlight, keep out of reach of children.
Formulations
- Tablets
- Capsules
- Chewable tablets
- Liquid formulations
AI-synthesized from BNF references - general information only, not a substitute for professional medical advice or the current BNF. Verify doses with a pharmacist.
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