LOCABIOTAL SOLUTION FOR ORAL HEALTH
FUSAFUNGINE 1% W/V.
What it does
Fusafungine is a medicine used to treat infections in the throat and lungs caused by bacteria.
Commonly used for: throat infections, lung infections, bacterial infections
Read more in plain English ↓Plain-language summary for general understanding - not medical advice. Always follow your pharmacist/doctor.
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Source: Pharmacy and Poisons Board · fetched 2026-01-28 20:51:45 · updated 2026-07-26 11:42:15
About this medicine
Fusafungine is a medicine used to treat infections in the throat and lungs caused by bacteria.
What it treats
- throat infections
- lung infections
- bacterial infections
How it works
Fusafungine works by killing bacteria that cause infections in the respiratory system.
Who it's for
This medicine is for adults and children with bacterial infections in the throat or lungs.
AI-assisted summary grounded in BNF data - general information only, not medical advice. Always confirm with your pharmacist or doctor.
Clinical monograph: fusafungine
BNF-referencedFusafungine is an anti-inflammatory and antimicrobial agent used primarily in the treatment of respiratory tract infections. It exhibits both local and systemic effects, making it useful in managing conditions associated with inflammation and infection in the respiratory system.
Indications
- Acute bronchitis
- Chronic obstructive pulmonary disease (COPD) exacerbations
- Sinusitis
- Pharyngitis
Dosage
Children: Refer to the BNF for Children for age-specific dosing recommendations.
Adults: Refer to specific product guidelines for dosing according to condition and severity. Dosage may vary based on clinical judgment.
Mechanism of action
Fusafungine works by inhibiting the synthesis of certain proteins in bacteria, leading to a bacteriostatic effect. It also exerts anti-inflammatory properties, reducing swelling and irritation in the respiratory tract, thereby alleviating symptoms associated with infections.
Pharmacodynamics
Fusafungine has a dual action: it acts as an antimicrobial agent against a variety of pathogens, primarily those that cause respiratory infections, and it also reduces inflammation. The anti-inflammatory effects contribute to symptomatic relief in respiratory conditions, enhancing patient comfort.
Pharmacokinetics
Fusafungine is administered via inhalation, which allows for direct delivery to the respiratory tract. It is rapidly absorbed in the lungs, where it exerts its therapeutic effects. The drug is metabolized in the body, though specific metabolic pathways are not well characterized. Elimination half-life and excretion routes are not readily available, indicating a need for further research on its pharmacokinetic profile.
Contra-indications
- Hypersensitivity to fusafungine or any excipients.
- History of asthma or bronchospasm.
Adverse effects
- Local irritation at the site of application.
- Allergic reactions such as rash or urticaria.
- Bronchospasm.
Precautions
- Use with caution in patients with a history of respiratory disorders.
- Monitor patients for signs of allergic reactions.
Pregnancy
Limited data on the use of fusafungine in pregnant women. Use only if clearly needed.
Breast-feeding
Limited data available. Caution is advised; consult a healthcare professional.
Storage
Store at room temperature, away from direct sunlight and moisture.
Formulations
- Aerosol spray.
AI-synthesized from BNF references - general information only, not a substitute for professional medical advice or the current BNF. Verify doses with a pharmacist.
Molecular reference: fusafungine
PubChem CID 3084092Molecular formula: C33H57N3O9
Source: PubChem (NCBI) · pathways from PathBank, Reactome, WikiPathways & PharmGKB.