What it does
Mercuric is a chemical compound that has been used in various medical applications, but it is important to be aware of its risks.
Commonly used for: mercury poisoning, certain skin conditions
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Sourcing - Kenya onlyRegistration & product details
Source: Botswana Medicines Regulatory Authority · fetched 2026-04-15 20:42:16 · updated 2026-05-12 08:02:54
About this medicine
Mercuric is a chemical compound that has been used in various medical applications, but it is important to be aware of its risks.
What it treats
- mercury poisoning
- certain skin conditions
How it works
Mercuric works by interacting with biological systems, but it can be toxic and harmful if not used properly.
Who it's for
This treatment may be considered for individuals with specific conditions as determined by a healthcare professional.
Cautions
- • Can be toxic if misused.
- • Not recommended for long-term use.
AI-assisted summary grounded in BNF data - general information only, not medical advice. Always confirm with your pharmacist or doctor.
Clinical monograph: mercuric
Mercuric compounds, often referred to in the context of mercuric chloride or mercuric oxide, are inorganic mercury salts that have been historically used in various medicinal and industrial applications. Due to their toxic properties, their use in medicine is now highly restricted. Mercuric chloride, for example, has been used as a disinfectant and antiseptic, but it is also known for its severe toxicity and potential for causing mercury poisoning.
Indications
- Historically used as a disinfectant
- Antiseptic
- Treatment of certain infections (now largely abandoned due to toxicity)
Dosage
Children: Specific dosing is not provided due to safety concerns and the potential for toxicity. Refer to appropriate clinical guidelines for dosing if applicable.
Adults: Specific dosing is not provided due to safety concerns and the potential for toxicity. Refer to appropriate clinical guidelines for dosing if applicable.
Mechanism of action
Mercuric compounds exert their effects primarily through the inhibition of sulfhydryl (thiol) groups in proteins and enzymes, leading to disruption of cellular functions. This interaction can affect various biochemical pathways, including those involved in cellular respiration and metabolism.
Pharmacodynamics
The pharmacodynamics of mercuric compounds is characterized by their ability to bind to cellular proteins, leading to alterations in enzymatic activity and disruption of cellular homeostasis. The toxic effects manifest in various organ systems, particularly the kidneys, nervous system, and gastrointestinal tract. Symptoms of mercury toxicity include tremors, memory loss, neuromuscular effects, and renal impairment.
Pharmacokinetics
Mercuric compounds are poorly absorbed from the gastrointestinal tract, but once absorbed, they can distribute widely throughout the body, accumulating in the kidneys, liver, and brain. The half-life of mercury in the body is prolonged, ranging from weeks to months, depending on the compound and individual factors. Excretion primarily occurs via the kidneys, with a small amount eliminated through feces and exhalation.
Contra-indications
- Hypersensitivity to mercuric compounds
- Severe renal impairment
- Active gastrointestinal disease
Adverse effects
- Nephrotoxicity
- Gastrointestinal disturbances (nausea, vomiting, diarrhea)
- Neurological effects (tremors, mood changes, cognitive impairment)
- Dermatitis
- Allergic reactions
- Hematological effects (anemia, leukopenia)
Interactions
- May interact with other nephrotoxic agents, increasing the risk of kidney damage
- Chelating agents like dimercaprol may be used in cases of poisoning but should be used cautiously
Precautions
- Use with caution in patients with pre-existing renal disease
- Monitor renal function regularly during treatment
- Avoid exposure in occupational settings due to potential for toxicity
Pregnancy
Mercuric compounds are contraindicated during pregnancy due to potential fetal toxicity and teratogenic effects.
Breast-feeding
Mercuric compounds should be avoided during breastfeeding due to the risk of excretion in breast milk and potential harm to the nursing infant.
Storage
Store in a tightly closed container, protected from light, at room temperature, away from moisture and incompatible substances.
Formulations
- Mercuric chloride
- Mercuric iodide
- Mercuric sulfide
AI-synthesized from BNF references - general information only, not a substitute for professional medical advice or the current BNF. Verify doses with a pharmacist.
This drug in other countries
The same active ingredient registered across other registries we cover - including different brands.