Registered Malawi · PMRA

PINKOO-GRIPE-WATER COMBINATION PRODUCT LIQUID

PURIFIED SARJIKAKSHARA (SODIUM BICARBONATE)

PMPB/PL303/12 LIQUID

What it does

Purified ingredients are often used in various medicines to ensure safety and effectiveness by removing impurities.

Commonly used for: various medical conditions

Read more in plain English ↓

Plain-language summary for general understanding - not medical advice. Always follow your pharmacist/doctor.

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Answers come only from this medicine's registration record, BNF monograph and interaction data - not medical advice.

Medicine sourcing is available in Kenya only. We don't sell or dispense medicines - licensed pharmacies do.

Sourcing - Kenya only

Registration & product details

Registration no.
PMPB/PL303/12
Registration date
23/07/2013
Expiry date
31/03/2025
Status
Registered
Active ingredient
PURIFIED SARJIKAKSHARA (SODIUM BICARBONATE)
Dosage form
LIQUID
Strength
-
Pack size
-
Therapeutic class
-
Manufacturer / MAH
-
Applicant / LTR
-
Country of origin
-

Source: Pharmacy and Medicines Regulatory Authority · fetched 2026-04-21 17:37:40 · updated 2026-09-29 04:33:05

Disclaimer: This information is sourced from Pharmacy and Medicines Regulatory Authority (Malawi). Always consult a qualified healthcare professional before using any medication.

About purified

Purified ingredients are often used in various medicines to ensure safety and effectiveness by removing impurities.

What it treats

  • various medical conditions

How it works

Purified ingredients help in delivering the intended effects of the medicine without the risk of contaminants.

Who it's for

People who need medications with safe and effective ingredients.

AI-assisted summary grounded in BNF data - general information only, not medical advice. Always confirm with your pharmacist or doctor.

About sarjikakshara

Sarjikakshara is a natural substance used in traditional medicine.

What it treats

  • digestive issues
  • stomach acidity
  • gastritis

How it works

It helps balance stomach acidity and supports digestion.

Who it's for

It is suitable for adults experiencing digestive discomfort.

AI-assisted summary grounded in BNF data - general information only, not medical advice. Always confirm with your pharmacist or doctor.

Clinical monograph: purified

Purified refers to a substance that has been processed to remove impurities, contaminants, or unwanted substances, resulting in a more concentrated and effective form of the original compound. In pharmacology, purified compounds are often used to enhance therapeutic efficacy and reduce adverse effects. The purification process can apply to a variety of substances, including drugs, biological products, and chemical compounds.

Dosage

Children: Refer to specific drug formulations and product labels as purified substances can vary widely in their use and dosing.

Adults: Refer to specific drug formulations and product labels as purified substances can vary widely in their use and dosing.

Mechanism of action

The mechanism of action for purified compounds varies widely depending on the specific substance. Generally, purified drugs exert their effects by interacting with specific biological targets, such as receptors, enzymes, or ion channels, leading to a desired therapeutic effect. This interaction can involve binding to receptors to activate or inhibit signaling pathways, modulating enzymatic activity, or altering physiological processes.

Pharmacodynamics

Pharmacodynamics describes the effects of a drug on the body and the relationship between drug concentration and effect. For purified drugs, this can involve dose-response relationships and the time course of their action. The purified form often enhances potency and reduces variability in response among patients, which can lead to more predictable therapeutic outcomes. The overall effect is determined by the drug's affinity for its target, the efficacy of the drug-receptor interaction, and the downstream signaling pathways activated as a result of this interaction.

Pharmacokinetics

Pharmacokinetics involves the absorption, distribution, metabolism, and excretion (ADME) of a drug. For purified substances, absorption can be more efficient due to the absence of impurities that may affect solubility or stability. Distribution may also be enhanced, leading to higher bioavailability. Metabolism can be influenced by the structure of the purified compound, as it may be metabolized more readily by liver enzymes. Excretion typically occurs through the kidneys or liver, depending on the molecular characteristics of the purified drug.

Pregnancy

Consult with a healthcare professional, as the safety of purified forms of medications during pregnancy may vary depending on the specific substance.

Breast-feeding

Consult with a healthcare professional, as the safety of purified forms of medications during breastfeeding may vary depending on the specific substance.

Storage

Store in a cool, dry place, away from light and moisture, and keep out of reach of children.

AI-synthesized from BNF references - general information only, not a substitute for professional medical advice or the current BNF. Verify doses with a pharmacist.

Clinical monograph: sarjikakshara

Sarjikakshara is a traditional Ayurvedic formulation primarily composed of the ashes of specific plants and minerals. It is known for its alkalizing properties and is typically used in the management of conditions related to excess acidity, such as peptic ulcers and gastroesophageal reflux disease (GERD). The preparation is believed to enhance digestive fire and improve metabolic processes.

Indications

  • Peptic ulcers
  • Gastroesophageal reflux disease (GERD)
  • Acid indigestion
  • Dyspepsia
  • Acid-related gastrointestinal disorders

Dosage

Children: Paediatric dosing should be determined by qualified practitioners, considering the child's age, weight, and specific condition. Refer to Ayurvedic guidelines for appropriate dosing in children.

Adults: Dosage typically varies based on practitioner recommendations, preparation form, and individual patient needs. It is essential to consult traditional Ayurvedic practitioners or relevant resources for specific dosing guidelines.

Mechanism of action

Sarjikakshara is thought to work by neutralizing gastric acid, thereby increasing the pH of the stomach contents. This alkalizing effect may reduce irritation of the gastric mucosa and promote healing of ulcers. Additionally, it is believed to stimulate the secretion of digestive enzymes, enhancing overall digestive function.

Pharmacodynamics

The pharmacodynamics of Sarjikakshara involve its ability to balance the body's pH levels, particularly in the gastrointestinal tract. By reducing acidity, it helps to alleviate symptoms of acid-related disorders. Its mineral content may contribute to its therapeutic effects, including promoting mucosal healing and improving gut motility.

Pharmacokinetics

Pharmacokinetic data specific to Sarjikakshara is limited due to its traditional formulation and lack of extensive clinical research. However, it is generally considered to act locally in the gastrointestinal tract. Its components are likely to be absorbed at different rates depending on their solubility and the gastrointestinal environment, but specific absorption, distribution, metabolism, and excretion (ADME) details are not well-documented.

Pregnancy

There is limited information available regarding the safety of sarjikakshara during pregnancy. It is advisable to use caution and consult with a healthcare provider before use.

Breast-feeding

Limited information is available on the excretion of sarjikakshara in breast milk. Caution is advised when administering to breastfeeding mothers.

Storage

Store in a cool, dry place, away from direct sunlight and moisture. Keep out of reach of children.

AI-synthesized from BNF references - general information only, not a substitute for professional medical advice or the current BNF. Verify doses with a pharmacist.

This drug in other countries

The same active ingredient registered across other registries we cover - including different brands.