RESFLO 282.5MG ORAL POWDER
SACCHROMYCES BOULARDII (LYPHOLIZED)
What it does
Boulardii is a type of beneficial yeast that helps maintain gut health.
Commonly used for: diarrhea, gastrointestinal infections, irritable bowel syndrome (IBS)
Read more in plain English ↓Plain-language summary for general understanding - not medical advice. Always follow your pharmacist/doctor.
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Sourcing - Kenya onlyRegistration & product details
Source: Pharmacy and Medicines Regulatory Authority · fetched 2026-04-21 17:37:40 · updated 2026-09-26 04:30:27
About boulardii
Boulardii is a type of beneficial yeast that helps maintain gut health.
What it treats
- diarrhea
- gastrointestinal infections
- irritable bowel syndrome (IBS)
How it works
Boulardii supports healthy digestion by promoting the growth of good bacteria in the gut.
Who it's for
It is suitable for people experiencing digestive issues or looking to maintain gut health.
AI-assisted summary grounded in BNF data - general information only, not medical advice. Always confirm with your pharmacist or doctor.
About sacchromyces
Saccharomyces is a type of yeast often used as a probiotic to support gut health.
What it treats
- digestive issues
- irritable bowel syndrome (IBS)
- diarrhea
- restoring gut flora
How it works
It helps balance the bacteria in your gut, which can improve digestion and overall gut health.
Who it's for
It is suitable for people looking to support their digestive health or recover from digestive disturbances.
AI-assisted summary grounded in BNF data - general information only, not medical advice. Always confirm with your pharmacist or doctor.
Clinical monograph: boulardii
Saccharomyces boulardii is a probiotic yeast used to support gastrointestinal health. It is known for its ability to restore the natural flora of the gut, particularly following disturbances such as antibiotic therapy or episodes of diarrhoea. Boulardii can help in the prevention and treatment of various forms of diarrhoea, including antibiotic-associated diarrhoea and acute infectious diarrhoea. It may also play a role in managing conditions like irritable bowel syndrome and inflammatory bowel diseases.
Indications
- Antibiotic-associated diarrhoea
- Acute infectious diarrhoea
- Clostridium difficile infection
- Irritable bowel syndrome
- Inflammatory bowel disease
Dosage
Children: Refer to the specific product guidelines for dosing, as it may vary based on formulation and indication.
Adults: Refer to the specific product guidelines for dosing, as it may vary based on formulation and indication.
Mechanism of action
Saccharomyces boulardii exerts its beneficial effects by several mechanisms. It helps to restore the intestinal microbiota balance, enhances the intestinal barrier function, and modulates immune responses. It produces short-chain fatty acids and other metabolites that can inhibit pathogen adherence and growth. Boulardii also stimulates the production of mucin, which is important for maintaining the integrity of the gut lining.
Pharmacodynamics
The pharmacodynamic properties of Saccharomyces boulardii are primarily related to its ability to interact with the gut microbiota and immune system. It exhibits antimicrobial activity against various pathogens, including Clostridium difficile and Escherichia coli, and can modulate inflammatory responses in the gut. Boulardii is also known to enhance the absorption of nutrients and improve gut motility.
Pharmacokinetics
Saccharomyces boulardii is not absorbed systemically; rather, it acts locally within the gastrointestinal tract. After oral administration, it survives the gastric environment and colonizes the intestines transiently, exerting its effects. The viability of boulardii is critical for its action, and it is typically taken as a live yeast culture. The duration of action is influenced by the intestinal transit time and the presence of competing microorganisms.
Adverse effects
- Gas
- Bloating
- Abdominal discomfort
- Diarrhea
Precautions
- Use with caution in immunocompromised patients
- Consider potential for fungal infections in at-risk populations
Pregnancy
No adequate studies in pregnant women are available, consult healthcare provider before use.
Breast-feeding
Generally considered safe, but consult healthcare provider for individual assessment.
Storage
Store in a cool, dry place. Keep out of reach of children.
Formulations
- Capsules
- Powder for reconstitution
- Tablets
AI-synthesized from BNF references - general information only, not a substitute for professional medical advice or the current BNF. Verify doses with a pharmacist.
Clinical monograph: sacchromyces
Saccharomyces, commonly known as baker's yeast, is a genus of fungi that is widely used in baking, brewing, and fermentation processes. It is also recognized for its probiotic properties and is used as a dietary supplement to promote gastrointestinal health. Saccharomyces boulardii, a specific strain, is often utilized for its potential benefits in managing diarrhea and other gastrointestinal disorders.
Indications
- Antibiotic-associated diarrhea
- Infectious diarrhea
- Irritable bowel syndrome
- Maintenance of gut flora
- Support for gastrointestinal health
Dosage
Children: Refer to specific product guidelines or consult a healthcare professional for appropriate dosing instructions.
Adults: Refer to specific product guidelines or consult a healthcare professional for appropriate dosing instructions.
Mechanism of action
Saccharomyces works by exerting beneficial effects on gut microbiota, enhancing intestinal barrier function, and modulating immune responses. It can inhibit pathogenic bacteria and promote the growth of beneficial microorganisms, contributing to a balanced gut environment.
Pharmacodynamics
The pharmacodynamics of Saccharomyces involves its ability to maintain intestinal homeostasis, reduce inflammation, and restore the gut flora after disturbances such as antibiotic use. It may help in reducing the duration and severity of diarrhea, particularly antibiotic-associated diarrhea and infectious diarrhea.
Pharmacokinetics
As a probiotic, Saccharomyces is not absorbed systemically; its effects are primarily local within the gastrointestinal tract. It survives passage through the stomach and colonizes the intestines, where it exerts its effects. The metabolism of Saccharomyces involves fermentation of carbohydrates to produce short-chain fatty acids and other metabolites beneficial for gut health.
Adverse effects
- Bloating
- Gas
- Constipation
- Nausea
Interactions
- May interact with antifungal medications due to similar mechanisms
- Use with caution in patients on immunosuppressants
Precautions
- Use with caution in patients with compromised immune systems
- Avoid in individuals with a history of yeast allergies
- Monitor for gastrointestinal symptoms
Pregnancy
Considered safe in pregnancy, but consult a healthcare provider before use.
Breast-feeding
Generally regarded as safe during breastfeeding, but consult a healthcare provider.
Storage
Store in a cool, dry place, away from direct sunlight.
Formulations
- Capsules
- Powder
- Tablets
- Liquid
AI-synthesized from BNF references - general information only, not a substitute for professional medical advice or the current BNF. Verify doses with a pharmacist.
This drug in other countries
The same active ingredient registered across other registries we cover - including different brands.