Is RL-500ML registered in Rwanda?

RL-500ML is recorded with registration status “Registered” in Rwanda, registration number Rwanda FDA-HMP-MA- 1337, based on Rwanda FDA data.

Who manufactures RL-500ML?

RL-500ML is manufactured by Amanta Healthcare.

Reference image
(lactate · DailyMed)

Registered Rwanda · Rwanda FDA

RL-500ML

Q: What is the active ingredient in RL-500ML?

RL-500ML contains Sodium lactate 0.320% w/v, Sodium chloride 0.600 % w/v, Potassium chloride 0.040 % w/v, Calcium chloride 0.027 % w/v, dosage form Solution for Intravenous Infusion.

Sodium lactate 0.320% w/v, Sodium chloride 0.600 % w/v, Potassium chloride 0.040 % w/v, Calcium chloride 0.027 % w/v

Rwanda FDA-HMP-MA- 1337 Solution for Intravenous Infusion 0.320% w/v, 0.600 % w/v, 0.040 % w/v, 0.027 % w/v genito urinary system and sex hormones INN generic

What it does

Lactate is a substance used in medical settings to help manage certain conditions related to acid-base balance in the body.

Commonly used for: metabolic acidosis, lactic acidosis, supporting hydration

Registration & product details

Registration no.

Rwanda FDA-HMP-MA- 1337

Registration date

18/05/2024

Expiry date

17/05/2029

Status

Registered

Active ingredient

Sodium lactate 0.320% w/v, Sodium chloride 0.600 % w/v, Potassium chloride 0.040 % w/v, Calcium chloride 0.027 % w/v

Dosage form

Solution for Intravenous Infusion

Strength

0.320% w/v, 0.600 % w/v, 0.040 % w/v, 0.027 % w/v

Pack size

500 ml bottle

Therapeutic class

ATC class (WHO)

G01AD - Organic acids

Drug group

GENITO URINARY SYSTEM AND SEX HORMONES

RxNorm RxCUI

114202

Manufacturer / MAH

Amanta Healthcare

Applicant / LTR

AMANTA HEALTHCARE LIMITED, INDIA

Country of origin

INDIA

Manufacturer location

8th Floor, Shaligram Corporates, Chhanalal Joshi Marg, Ambli, Ahmedabad, Gujarat 380058, India

Source: Rwanda Food and Drugs Authority · fetched 2026-03-11 22:07:13 · updated 2026-09-17 02:30:43

Disclaimer: This information is sourced from Rwanda Food and Drugs Authority (Rwanda). Always consult a qualified healthcare professional before using any medication.

About this medicine

Lactate is a substance used in medical settings to help manage certain conditions related to acid-base balance in the body.

What it treats

metabolic acidosis
lactic acidosis
supporting hydration

How it works

Lactate helps to correct acid levels in the body, providing energy to cells and supporting metabolic processes.

Who it's for

Adults and children who have conditions causing an imbalance in body acids.

AI-assisted summary grounded in BNF data - general information only, not medical advice. Always confirm with your pharmacist or doctor.

Clinical monograph: lactate

BNF-referenced

Lactate, the anion of lactic acid, is a key intermediate in metabolic processes, primarily produced during anaerobic glycolysis. It serves as an important energy source, particularly for heart and skeletal muscle, and plays a crucial role in the Cori cycle, where it is converted back to glucose in the liver. Elevated lactate levels can indicate anaerobic metabolism, often observed in conditions such as sepsis, shock, or strenuous exercise.

Indications

Metabolic acidosis
Lactic acidosis
Energy substrate in critical illness
Monitoring tissue perfusion and oxygenation

Dosage

Children: Refer to the BNF for Children for appropriate dosing in paediatric patients.

Adults: Refer to specific guidelines based on clinical context as dosing is highly variable and situation-dependent.

Mechanism of action

Lactate acts as a signaling molecule and energy substrate in various physiological and pathological processes. It is involved in the modulation of several metabolic pathways, including the Cori cycle and Krebs cycle. Lactate also participates in metabolic reprogramming, especially in cancer cells, where it can promote tumor growth and survival by providing an alternative energy source and influencing cellular signaling pathways such as the PI3K/AKT/mTOR pathway.

Pharmacodynamics

Lactate plays a vital role in energy metabolism. It can be oxidized back to pyruvate by lactate dehydrogenase, entering the Krebs cycle for ATP production. In addition to serving as an energy substrate, lactate impacts pH regulation and can influence the function of various immune cells. Its levels can indicate the state of oxygen delivery and utilization in tissues, thus serving as a marker for metabolic stress.

Pharmacokinetics

Lactate is produced primarily in the cytoplasm during glycolysis, with its concentration in the blood reflecting the balance between production and clearance. It is metabolized predominantly in the liver, where it can be converted back to glucose or utilized in the Krebs cycle. Lactate levels can vary based on factors such as exercise, tissue hypoxia, and metabolic conditions.

Pregnancy

Lactate is generally regarded as safe during pregnancy as it is a naturally occurring metabolite in the body, but specific clinical advice should be sought.

Breast-feeding

Lactate is considered safe during breastfeeding as it is a normal component of human metabolism, but consult a healthcare provider for personalized advice.

Storage

Store in a cool, dry place away from direct sunlight. Keep out of reach of children.

PubChem / pathway

AI-synthesized from BNF references - general information only, not a substitute for professional medical advice or the current BNF. Verify doses with a pharmacist.

Molecular reference: lactate

PubChem CID 91435

Molecular formula: C3H5O3-

Biological pathways

Cori cycle WikiPathways PI3K/AKT/mTOR - vitamin D3 signaling WikiPathways Krebs cycle disorders WikiPathways Proximal tubule transport WikiPathways Glycolysis in senescence WikiPathways NAD metabolism in oncogene-induced senescence and mitochondrial dysfunction-associated senescence WikiPathways Interactions of natural killer cells in pancreatic cancer WikiPathways Metabolic reprogramming in pancreatic cancer WikiPathways Carnosine metabolism of glial cells WikiPathways Lactate shuttle in glial cells WikiPathways Affected pathways in Duchenne muscular dystrophy WikiPathways Warburg effect modulated by deubiquitinating enzymes and their substrates WikiPathways

Source: PubChem (NCBI) · pathways from PathBank, Reactome, WikiPathways & PharmGKB.

This drug in other countries

The same active ingredient registered across other registries we cover - including different brands.

Ghana 45 products

View all 45 in Ghana →

Kenya 34 products

View all 34 in Kenya →

Botswana 1 product

RINGER LACTATE FRESENIUS · Fresenius Kabi