What it does
Scabsol is a medication used to treat scabies, a skin condition caused by tiny mites that burrow into the skin.
Commonly used for: scabies
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Source: Pharmacy and Poisons Board · fetched 2026-01-28 20:40:20 · updated 2026-07-26 11:30:59
About this medicine
Scabsol is a medication used to treat scabies, a skin condition caused by tiny mites that burrow into the skin.
What it treats
- scabies
How it works
Scabsol works by killing the mites and their eggs, helping to relieve itching and irritation.
Who it's for
This medication is suitable for adults and children who have been diagnosed with scabies.
AI-assisted summary grounded in BNF data - general information only, not medical advice. Always confirm with your pharmacist or doctor.
Clinical monograph: scabsol
Scabsol is a topical medication used primarily for the treatment of scabies, a contagious skin infestation caused by the Sarcoptes scabiei mite. It contains benzyl benzoate as its active ingredient, which acts as a scabicidal agent, effectively eradicating the mites and alleviating the associated itching and skin irritation.
Indications
- Scabies
- Pediculosis (lice infestation)
Dosage
Children: Use as directed by a healthcare professional, typically applying to the affected areas of the skin, ensuring full coverage. Refer to specific guidelines for age-related dosing.
Adults: Apply the lotion to the affected areas of the skin, ensuring full coverage. Leave on for the recommended duration as per the product instructions, usually overnight, before washing off.
Mechanism of action
Benzyl benzoate, the active ingredient in Scabsol, exerts its effect by acting as a neurotoxin to the parasite. It disrupts the function of the mite’s central nervous system, leading to paralysis and death. The compound also has a mild solvent effect on the cuticle of the mites, enhancing its penetration and efficacy.
Pharmacodynamics
Benzyl benzoate has been shown to possess scabicidal properties, effectively killing the mites that cause scabies. It also has antiparasitic effects against other ectoparasites. The onset of action is relatively rapid, with relief from itching often noted shortly after application, although complete eradication of the infestation may take several days.
Pharmacokinetics
When applied topically, benzyl benzoate is absorbed through the skin, but its systemic absorption is minimal. The peak plasma concentration is reached shortly after application, but due to its high lipophilicity, it primarily remains localized at the site of application. The half-life and elimination pathways are not well characterized due to its limited systemic absorption.
Adverse effects
- Skin irritation
- Burning sensation
- Erythema
- Itching
- Allergic reactions
Precautions
- Avoid contact with eyes and mucous membranes
- Use with caution in patients with sensitive skin or allergies
- Do not apply to broken or inflamed skin
Pregnancy
Safety in pregnancy has not been established. Use only if clearly needed and prescribed.
Breast-feeding
Use with caution. Consult a healthcare professional before use.
Storage
Store at room temperature, away from moisture and heat. Keep out of reach of children.
Formulations
- Cream
- Lotion
- Emulsion
AI-synthesized from BNF references - general information only, not a substitute for professional medical advice or the current BNF. Verify doses with a pharmacist.