What it does
Pine is a natural substance often used for its potential health benefits.
Commonly used for: respiratory issues, inflammation, antioxidant support
Read more in plain English ↓Plain-language summary for general understanding - not medical advice. Always follow your pharmacist/doctor.
Ask about this medicine
Answers come only from this medicine's registration record, BNF monograph and interaction data - not medical advice.
Medicine sourcing is available in Kenya only. We don't sell or dispense medicines - licensed pharmacies do.
Sourcing - Kenya onlyRegistration & product details
Source: Tanzania Medicines and Medical Devices Authority · fetched 2026-03-11 23:44:05 · updated 2026-10-19 03:00:45
About this medicine
Pine is a natural substance often used for its potential health benefits.
What it treats
- respiratory issues
- inflammation
- antioxidant support
How it works
Pine may help reduce inflammation and support the immune system due to its natural compounds.
Who it's for
Pine can be used by adults looking for natural ways to support their health, particularly for respiratory and inflammatory conditions.
AI-assisted summary grounded in BNF data - general information only, not medical advice. Always confirm with your pharmacist or doctor.
Clinical monograph: pine
Pine, specifically pine bark extract, is derived from the inner bark of the pine tree, primarily the Pinus pinaster species. It is rich in proanthocyanidins, which are powerful antioxidants. Pine bark extract is often used as a dietary supplement for its potential health benefits, including improving circulation and reducing inflammation.
Indications
- Chronic venous insufficiency
- Osteoarthritis
- Hypertension
- Diabetes
- Cardiovascular health
- Antioxidant support
Dosage
Children: Refer to a healthcare professional or product guidelines for pediatric dosing, as safety and efficacy have not been well established in children.
Adults: Refer to the specific product guidelines, as dosages can vary based on the formulation and concentration of the extract.
Mechanism of action
The active compounds in pine bark extract, particularly proanthocyanidins, exert their effects through several mechanisms. They enhance nitric oxide production, which leads to vasodilation and improved blood flow. Additionally, they inhibit the oxidation of low-density lipoprotein (LDL) cholesterol, thus contributing to cardiovascular health. The antioxidant properties help reduce oxidative stress and inflammation by scavenging free radicals and modulating inflammatory pathways.
Pharmacodynamics
Pine bark extract displays a range of pharmacodynamic effects, including vasodilatory, anti-inflammatory, and antioxidant properties. These effects can lead to improved circulation, reduced symptoms of chronic venous insufficiency, and potential benefits in conditions associated with oxidative stress. The anti-inflammatory effects may also contribute to pain relief in osteoarthritis and other inflammatory conditions.
Pharmacokinetics
The pharmacokinetics of pine bark extract are influenced by its route of administration, typically oral. After ingestion, proanthocyanidins are absorbed in the gastrointestinal tract and distributed throughout the body. They undergo metabolic conversion in the liver, with a half-life that can vary based on individual metabolism and formulation. Elimination occurs primarily through urine, with metabolites detectable for several hours post-administration.
Adverse effects
- Allergic reactions
- Skin irritation
- Headache
- Gastrointestinal disturbances
Precautions
- Use with caution in individuals with known allergies to pine products.
- Monitor for allergic reactions in sensitive individuals.
Pregnancy
Pine products should be used with caution during pregnancy. Limited data is available regarding the safety of pine in pregnancy, consult a healthcare provider before use.
Breast-feeding
Caution is advised when using pine products while breastfeeding. Consult a healthcare provider for safety information.
Storage
Store in a cool, dry place away from direct sunlight. Keep out of reach of children.
Formulations
- Essential oil
- Extracts
- Topical ointments
AI-synthesized from BNF references - general information only, not a substitute for professional medical advice or the current BNF. Verify doses with a pharmacist.
This drug in other countries
The same active ingredient registered across other registries we cover - including different brands.