SUPRAPROCT CREAM
TRIBENOSIDELDOCAINE HCL
What it does
Tribenosideldocaine is a medication that helps relieve pain and discomfort, particularly in conditions involving the blood vessels and nerves.
Commonly used for: pain relief, venous disorders, neuropathic pain
Read more in plain English ↓Plain-language summary for general understanding - not medical advice. Always follow your pharmacist/doctor.
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Source: Pharmacy and Poisons Board · fetched 2026-01-28 21:02:05 · updated 2026-07-26 13:44:25
About this medicine
Tribenosideldocaine is a medication that helps relieve pain and discomfort, particularly in conditions involving the blood vessels and nerves.
What it treats
- pain relief
- venous disorders
- neuropathic pain
How it works
It works by blocking pain signals and improving blood flow in affected areas.
Who it's for
It is suitable for adults experiencing pain related to blood vessel or nerve issues.
AI-assisted summary grounded in BNF data - general information only, not medical advice. Always confirm with your pharmacist or doctor.
Clinical monograph: tribenosideldocaine
Tribenoside is a pharmacological agent that combines the effects of a venotonic and an anesthetic. It is primarily used for the treatment of venous disorders and has properties that help improve venous tone and reduce symptoms associated with venous insufficiency. Dodecyl sulfate, a component of tribenoside, is known for its local anesthetic effects, providing relief from pain and discomfort in various medical conditions.
Indications
- Chronic venous insufficiency
- Hemorrhoids
- Varicose veins
- Superficial phlebitis
- Peripheral vascular disorders
Dosage
Children: Refer to the BNF for Children or specific product guidelines for appropriate dosing information.
Adults: Refer to the specific product guidelines or local protocols for appropriate dosing information.
Mechanism of action
Tribenoside exerts its effects primarily through its venotonic action, which enhances venous tone and promotes venous return. It works by modulating the permeability of blood vessels and improving microcirculation. The local anesthetic component, dodecyl sulfate, blocks sodium channels, preventing the initiation and conduction of nerve impulses, resulting in analgesia.
Pharmacodynamics
Tribenoside has both venotonic and analgesic properties. The venotonic effect is attributed to the stabilization of vascular permeability and enhancement of venous tone, resulting in decreased edema and improved symptoms of venous insufficiency such as heaviness, pain, and swelling. The analgesic effect provides relief from pain in conditions such as hemorrhoids or superficial phlebitis, contributing to improved patient comfort.
Pharmacokinetics
The pharmacokinetics of tribenoside are not extensively detailed in literature. However, it is generally believed that after administration, tribenoside is absorbed into the bloodstream, where it exerts its therapeutic effects. The metabolism and elimination pathways have not been fully characterized, but the duration of action is influenced by the pharmacodynamic properties of both the venotonic and anesthetic components.
Pregnancy
Safety in pregnancy has not been established, consult a healthcare provider before use.
Breast-feeding
Consult a healthcare provider before using during breastfeeding.
Storage
Store at room temperature, away from moisture and direct sunlight.
AI-synthesized from BNF references - general information only, not a substitute for professional medical advice or the current BNF. Verify doses with a pharmacist.