VAXIGRIP INFLUENZA VIRUS VACCINE SPLIT VIRION INACTIVATED PREFILLED SYRINGE INFLUENZA VACCINE (SPLIT VIRION INACTIVATED)
INFLUENZA AH1N1 INFLUENZA AH3N2 AND INFLUENZA B
What it does
Influenza is a viral infection that affects the respiratory system, often causing fever, cough, and body aches.
Commonly used for: influenza (flu)
Read more in plain English ↓Plain-language summary for general understanding - not medical advice. Always follow your pharmacist/doctor.
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Source: Pharmacy and Poisons Board · fetched 2026-01-28 21:15:08 · updated 2026-07-20 08:58:19
About this medicine
Influenza is a viral infection that affects the respiratory system, often causing fever, cough, and body aches.
What it treats
- influenza (flu)
How it works
Influenza viruses infect the respiratory tract, leading to symptoms like fever and cough.
Who it's for
This information is for individuals at risk of flu, including children, elderly, and those with weakened immune systems.
AI-assisted summary grounded in BNF data - general information only, not medical advice. Always confirm with your pharmacist or doctor.
Clinical monograph: influenza
Influenza, commonly known as the flu, is an infectious disease caused by the influenza virus, which affects the respiratory system. The flu can lead to mild to severe illness and can result in hospitalization and death. Vaccination is the primary method for preventing influenza, and antiviral medications can help treat the infection after it occurs.
Indications
- Prevention of influenza virus infection
- Reduction of the severity of influenza illness
- Protection for high-risk groups against influenza complications
Dosage
Children: Refer to the BNF for Children for specific dosing recommendations for paediatric patients based on age and health status.
Adults: Refer to the BNF for specific dosing recommendations for adult patients based on the type of vaccine and individual health status.
Mechanism of action
Influenza vaccines stimulate the immune system to produce antibodies against the influenza virus. When the body is exposed to the virus, these antibodies help to prevent infection or mitigate the severity of the disease. The vaccines may contain inactivated virus or live attenuated virus, depending on the formulation.
Pharmacodynamics
Upon administration of the influenza vaccine, the immune system recognizes the viral antigens and generates a specific immune response. This response includes the production of antibodies, primarily immunoglobulin G (IgG), which can neutralize the virus and prevent its replication. The response varies based on individual health status and age.
Pharmacokinetics
The pharmacokinetics of influenza vaccines vary by type. After intramuscular or subcutaneous administration, the vaccine components are absorbed into the systemic circulation, leading to the production of antibodies. Peak antibody levels typically occur within 2 to 4 weeks after vaccination. The half-life of antibodies can vary, but they generally persist for several months, providing immunity against future infections.
Interactions
- normal immunoglobulin + influenza vaccine live: Unknown (decreases efficacy)
Pregnancy
Influenza vaccination is recommended during pregnancy, especially in the second and third trimesters, as it protects both mother and fetus.
Breast-feeding
Influenza vaccination is safe during breastfeeding and provides passive immunity to the infant.
Storage
Influenza vaccines should be stored in a refrigerator at 2 to 8 degrees Celsius. Do not freeze.
AI-synthesized from BNF references - general information only, not a substitute for professional medical advice or the current BNF. Verify doses with a pharmacist.
This drug in other countries
The same active ingredient registered across other registries we cover - including different brands.
- DIPHTERIA,TETANUS,HEPATITIS B AND HAEMOPHILUS INFLUENZA TYPE B CONJUGATE VACCINE ADSORBED · Serum Institute Of India
- NEWFLEND ND H9 4000D CONCENTRATE FOR SUSPENSION FOR INJECTION (CELL-ASSOCIATED LIVE RECOMBINANT TURKEY HERPESVIRUS (RHVT/ND-H9) EXPRESSING THE FUSION PROTEIN OF NEWCASTLE DISEASE VIRUS AND THE HEMAGGLUTININ H9-SUBTYPE OF LOW PATHOGENIC AVIAN INFLUENZA) · Ceva-phylaxia