bosentan brands

4 registered brands containing bosentan in Kenya.

Bosentan 2D chemical structure

2D structure

Bosentan

PubChem CID 104865

Molecular formula: C27H29N5O6S

Endothelin-1 (ET-1) is a neurohormone, the effects of which are mediated by binding to ET<sub>A</sub> and ET<sub>B</sub> receptors in the endothelium and vascular smooth muscle. It displays a slightly higher affinity towards ET<sub>A</sub> receptors than ET<sub>B</sub> receptors. ET-1 concentrations are elevated in plasma and lung tissue of patients with pulmonary arterial hypertension, suggesting a pathogenic role for ET-1 in this disease. Bosentan is a specific and competitive antagonist at endothelin receptor types ET<sub>A</sub> and ET<sub>B</sub>.

Source: PubChem (NCBI) ยท compound 104865

All countries Kenya Tanzania Rwanda Zambia Uganda Malawi South Africa Zimbabwe Nigeria Ghana Botswana
Product Manufacturer Status Country
BOSETAN 125
125MG
 Surgilinks Registered Kenya
BOSETAN 62.5
62.5MG
 Surgilinks Registered Kenya
PULMOFIRST 125
125 MG
 Simba Pharmaceuticals Registered Kenya
PULMOFIRST 62.5
62.5 MG
 Simba Pharmaceuticals Registered Kenya