International reference: 1 US FDA recall for this ingredient

Marketed Without An Approved NDA/ANDA: The product contains undeclared sibutramine and phenolphthalein. Sibutramine and phenolphthalein are not currently marketed in the United States, making this product an unapproved new drug. (sinensis)

US-market enforcement records (OpenFDA), shown for reference - not specific to this product in Malawi.

Registered Malawi · PMRA

CORDYCEPS PLUS COMBINATION PRODUCT CAPSULE

CORDYCEPS SINENSIS MYCELIUM, RADIX GINSENG, CORNU CERVI PANTOTRICHUM

PMPB/PL400/2 CAPSULE

What it does

Cervi is a medicinal ingredient used in various treatments.

Commonly used for: General health support, Alternative medicine

Read more in plain English ↓

Plain-language summary for general understanding - not medical advice. Always follow your pharmacist/doctor.

Ask about this medicine

Answers come only from this medicine's registration record, BNF monograph and interaction data - not medical advice.

Medicine sourcing is available in Kenya only. We don't sell or dispense medicines - licensed pharmacies do.

Sourcing - Kenya only

Registration & product details

Registration no.
PMPB/PL400/2
Registration date
27/01/2015
Expiry date
30/06/2015
Status
Registered
Active ingredient
CORDYCEPS SINENSIS MYCELIUM, RADIX GINSENG, CORNU CERVI PANTOTRICHUM
Dosage form
CAPSULE
Strength
-
Pack size
-
Therapeutic class
-
RxNorm RxCUI
325526
Manufacturer / MAH
-
Applicant / LTR
-
Country of origin
-

Source: Pharmacy and Medicines Regulatory Authority · fetched 2026-04-21 17:37:42 · updated 2026-09-29 04:33:05

Disclaimer: This information is sourced from Pharmacy and Medicines Regulatory Authority (Malawi). Always consult a qualified healthcare professional before using any medication.

About cervi

Cervi is a medicinal ingredient used in various treatments.

What it treats

  • General health support
  • Alternative medicine

How it works

The exact way Cervi works is not fully understood, but it is believed to support health in different ways.

Who it's for

Cervi may be suitable for adults looking for health support.

AI-assisted summary grounded in BNF data - general information only, not medical advice. Always confirm with your pharmacist or doctor.

About cordyceps

Cordyceps is a natural supplement often used to boost energy and improve athletic performance.

What it treats

  • increased energy levels
  • improved physical performance
  • supporting immune health

How it works

Cordyceps may enhance the production of energy in the body and support overall health.

Who it's for

Adults looking for natural ways to increase energy and support their immune system.

AI-assisted summary grounded in BNF data - general information only, not medical advice. Always confirm with your pharmacist or doctor.

About cornu

Cornu is a natural substance used in traditional medicine.

What it treats

  • general health improvement
  • traditional healing

How it works

Cornu is believed to support the body's natural healing processes.

Who it's for

Adults seeking alternative or complementary health treatments.

AI-assisted summary grounded in BNF data - general information only, not medical advice. Always confirm with your pharmacist or doctor.

About ginseng

Ginseng is a herbal supplement that is often used to boost energy and improve overall health.

What it treats

  • fatigue
  • stress relief
  • improving mental performance

How it works

Ginseng is believed to enhance physical and mental performance by supporting the body's ability to adapt to stress and improve energy levels.

Who it's for

Ginseng is commonly used by adults looking for natural ways to increase energy and reduce stress.

AI-assisted summary grounded in BNF data - general information only, not medical advice. Always confirm with your pharmacist or doctor.

About mycelium

Mycelium is a type of fungus that is often used for various health purposes.

What it treats

  • supporting immune health
  • promoting gut health
  • providing nutrients

How it works

Mycelium may help improve health by providing beneficial compounds and supporting the body's natural functions.

Who it's for

Mycelium can be used by adults looking to boost their health or support their immune system.

AI-assisted summary grounded in BNF data - general information only, not medical advice. Always confirm with your pharmacist or doctor.

About pantotrichum

Pantotrichum is a medication used to treat various conditions related to hair and skin.

What it treats

  • hair loss (alopecia)
  • skin disorders

How it works

It helps by promoting healthy hair and skin growth.

Who it's for

This medication is suitable for individuals experiencing hair or skin issues.

AI-assisted summary grounded in BNF data - general information only, not medical advice. Always confirm with your pharmacist or doctor.

About radix

Radix is a herbal ingredient used in traditional medicine.

What it treats

  • general wellness
  • support for various health conditions

How it works

Radix is believed to support overall health and balance in the body.

Who it's for

This may be suitable for individuals looking for natural health support.

AI-assisted summary grounded in BNF data - general information only, not medical advice. Always confirm with your pharmacist or doctor.

About sinensis

Sinensis is a natural ingredient used for various health benefits.

What it treats

  • boosting immune system
  • reducing stress
  • improving energy levels

How it works

It helps the body to adapt to stress and promotes overall well-being.

Who it's for

It is suitable for adults looking to enhance their health and vitality.

AI-assisted summary grounded in BNF data - general information only, not medical advice. Always confirm with your pharmacist or doctor.

Clinical monograph: cervi

Cervi, also known as deer antler velvet, is a traditional supplement derived from the antlers of deer in their growth phase. It is often promoted for its potential health benefits, including improving athletic performance, enhancing recovery, and supporting joint health. The use of cervi is rooted in traditional medicine practices, particularly in Asian cultures, and is believed to contain various bioactive compounds such as growth factors, amino acids, and minerals.

Indications

  • Support for joint health
  • Enhancement of athletic performance
  • Aid in recovery from physical exertion
  • Potential immune system support
  • General health and wellness improvement

Dosage

Children: Refer to specific product guidelines as safety and efficacy in children have not been well established.

Adults: Refer to specific product guidelines as dosing can vary based on formulation and intended use.

Mechanism of action

Cervi is thought to exert its effects through several mechanisms, including the modulation of growth factor activity, which may enhance tissue repair and regeneration. It is believed to influence the endocrine system, potentially increasing levels of anabolic hormones. The exact pathways and molecular interactions remain understudied, but its constituents may also demonstrate antioxidant properties, contributing to overall health and wellness.

Pharmacodynamics

The pharmacodynamic properties of cervi involve its impact on biological systems, particularly in relation to growth and development. The growth factors present in cervi are believed to stimulate cell proliferation, enhance muscle recovery, and modulate immune responses. Its anti-inflammatory properties may aid in pain relief and joint health, making it a popular supplement among athletes and individuals with joint issues.

Pharmacokinetics

The pharmacokinetics of cervi are not well-defined due to a lack of comprehensive studies. However, it is understood that the active components may be absorbed through the gastrointestinal tract when ingested. The bioavailability of these components can vary based on the extraction method and formulation. Metabolism and excretion pathways remain largely unknown, necessitating further research to elucidate these aspects.

Pregnancy

Cervi is generally not recommended during pregnancy due to potential risks, and should only be used if the benefits outweigh the risks.

Breast-feeding

Cervi is not recommended during breastfeeding due to potential transmission of active compounds in breast milk.

Storage

Store in a cool, dry place away from direct sunlight. Keep out of reach of children.

AI-synthesized from BNF references - general information only, not a substitute for professional medical advice or the current BNF. Verify doses with a pharmacist.

Clinical monograph: cordyceps

Cordyceps is a genus of parasitic fungi known for its potential health benefits. It has been traditionally used in Chinese medicine for its adaptogenic properties, enhancing energy, stamina, and athletic performance. Cordyceps is also noted for its immunomodulatory effects and potential anti-inflammatory and antioxidant properties.

Indications

  • Chronic fatigue syndrome
  • Respiratory disorders
  • Immune system enhancement
  • Athletic performance enhancement
  • Potential adjunct in cancer treatment

Dosage

Children: There is insufficient clinical data to recommend specific dosing for pediatric populations. Consultation with a healthcare provider is advised.

Adults: Dosage varies widely depending on the formulation and intended use. General guidance suggests starting with a low dose and gradually increasing as tolerated, but specific dosing should be referenced from product labels or clinical studies.

Mechanism of action

Cordyceps exerts its effects primarily through modulation of the immune system and enhancement of cellular energy metabolism. It is believed to increase ATP production in cells, improve oxygen utilization, and enhance physical performance. Additionally, cordycepin, a bioactive compound within cordyceps, has been shown to inhibit tumor growth and promote apoptosis in cancer cells.

Pharmacodynamics

Cordyceps has been shown to improve exercise performance by increasing ATP production and enhancing oxygen usage in the muscles. Its immunomodulatory effects may help in enhancing the immune response, making it beneficial in conditions of immunosuppression. The antioxidant properties help in reducing oxidative stress, which is linked to many chronic diseases.

Pharmacokinetics

The pharmacokinetics of cordyceps are not well-defined in clinical studies. It is thought to be well-absorbed in the gastrointestinal tract, but specific data regarding its absorption, distribution, metabolism, and excretion are limited. The active compounds, such as cordycepin, are believed to undergo metabolism in the liver and may have varying half-lives depending on the formulation and dosage used.

Adverse effects

  • Nausea
  • Diarrhea
  • Dry mouth
  • Increased heart rate
  • Insomnia

Interactions

  • Anticoagulants - may enhance the effects of anticoagulant medications
  • Immunosuppressants - may stimulate immune function, potentially reducing the efficacy of immunosuppressive drugs

Precautions

  • Use with caution in individuals with autoimmune diseases due to potential immune system stimulation
  • Monitor for effects in patients with underlying health conditions

Pregnancy

Adequate studies in pregnant women are lacking; consult healthcare providers before use.

Breast-feeding

Limited data available; consult healthcare providers before use.

Storage

Store in a cool, dry place away from direct sunlight. Keep out of reach of children.

Formulations

  • Dried whole mushroom
  • Capsules
  • Powder extract
  • Liquid extract

AI-synthesized from BNF references - general information only, not a substitute for professional medical advice or the current BNF. Verify doses with a pharmacist.

Clinical monograph: cornu

Cornu is a traditional herbal remedy derived from various natural sources, often used in different cultures for its purported medicinal properties. It is commonly associated with the treatment of conditions such as respiratory disorders, fatigue, and potential anti-inflammatory effects. The exact composition can vary depending on the source and preparation method.

Indications

  • Respiratory disorders
  • Fatigue
  • Anti-inflammatory effects
  • General wellness

Dosage

Children: Refer to specific product guidelines, as dosing can vary widely based on preparation and intended use.

Adults: Refer to specific product guidelines, as dosing can vary widely based on preparation and intended use.

Mechanism of action

The specific mechanism of action for cornu is not well-defined in scientific literature. However, herbal remedies like cornu may exert their effects through modulation of immune responses, anti-inflammatory pathways, and antioxidant activities. Some components may influence neurotransmitter levels or promote circulation.

Pharmacodynamics

The pharmacodynamics of cornu are not fully understood due to the variability in its composition and preparation. Generally, it may enhance respiratory function and promote energy levels. Its anti-inflammatory properties could be attributed to the presence of bioactive compounds that inhibit pro-inflammatory mediators.

Pharmacokinetics

Pharmacokinetic data on cornu is limited. Absorption, distribution, metabolism, and excretion are likely influenced by the specific constituents of the preparation. Herbal components are typically metabolized by liver enzymes, and their effects can vary significantly based on individual factors such as age, sex, and health status.

Pregnancy

There is limited information available on the safety of cornu during pregnancy. Caution is advised, and it should only be used if the potential benefits justify any potential risks to the fetus.

Breast-feeding

There is insufficient data on the excretion of cornu into breast milk. Caution is recommended when administering it to nursing mothers.

Storage

Store in a cool, dry place, away from direct sunlight. Keep out of reach of children.

AI-synthesized from BNF references - general information only, not a substitute for professional medical advice or the current BNF. Verify doses with a pharmacist.

Clinical monograph: ginseng

Ginseng refers to a group of plants in the genus Panax, known for their potential health benefits. The most commonly used species are Panax ginseng (Asian ginseng) and Panax quinquefolius (American ginseng). Ginseng is often used as an adaptogen, believed to help the body resist stress and improve energy levels. It has also been studied for its effects on cognitive function, immune system support, and overall vitality.

Indications

  • Fatigue
  • Stress management
  • Cognitive enhancement
  • Immune support
  • General well-being

Dosage

Children: Refer to specific product guidelines, as dosing in children should be determined by a healthcare professional.

Adults: Refer to specific product guidelines, as dosing can vary based on formulation and intended use.

Mechanism of action

Ginseng is thought to exert its effects through several mechanisms, including modulation of the hypothalamic-pituitary-adrenal (HPA) axis, enhancement of antioxidant activity, and regulation of neurotransmitter levels. Ginsenosides, the active compounds in ginseng, may influence cellular signaling pathways, promote neuroprotection, and enhance immune responses.

Pharmacodynamics

The pharmacodynamic effects of ginseng are attributed primarily to its active constituents, ginsenosides, which interact with various receptors and enzymes in the body. These interactions can lead to increased energy metabolism, improved cognitive function, enhanced physical performance, and modulation of the immune system. Ginseng may also exhibit adaptogenic properties, helping the body to maintain homeostasis under stress.

Pharmacokinetics

Ginsenosides undergo extensive metabolism in the body, primarily by the liver. Bioavailability can vary significantly based on the specific ginsenoside and the method of administration. Ginseng is usually administered orally, with effects typically observed within several hours after ingestion. The elimination half-life of ginsenosides can vary based on the specific compound and individual metabolism, with some studies suggesting that effects may persist for several hours to days.

Adverse effects

  • Insomnia
  • Headache
  • Gastrointestinal disturbances
  • Nervousness
  • Hypertension
  • Allergic reactions

Interactions

  • May interact with anticoagulants (e.g., warfarin)
  • May enhance the effects of caffeine
  • May affect insulin levels and blood sugar control
  • Potential interaction with immunosuppressants

Precautions

  • Use with caution in patients with hypertension
  • May cause sleep disturbances; avoid use before bedtime
  • Should be used cautiously in patients with diabetes
  • Consult a healthcare provider before use in individuals with autoimmune conditions

Pregnancy

Limited data available. Generally not recommended due to potential hormonal effects.

Breast-feeding

Limited data available. Consult a healthcare provider before use.

Storage

Store in a cool, dry place, away from direct sunlight.

Formulations

  • Dried root
  • Powdered extract
  • Capsules
  • Tinctures
  • Teas

AI-synthesized from BNF references - general information only, not a substitute for professional medical advice or the current BNF. Verify doses with a pharmacist.

Clinical monograph: mycelium

Mycelium is the vegetative part of fungi, consisting of a mass of branching, thread-like structures called hyphae. It plays a crucial role in the growth and reproduction of fungi, serving as a means of nutrient absorption and interaction with the environment. In recent years, mycelium has gained attention for its potential applications in medicine, agriculture, and materials science, particularly due to its ability to decompose organic matter and improve soil health.

Indications

  • Immune support
  • Antimicrobial activity
  • Anti-inflammatory effects
  • Nutritional supplement
  • Potential adjunct in cancer therapy

Dosage

Children: Consult product-specific guidelines for children, as dosing may differ significantly based on age, weight, and health status.

Adults: General guidance suggests consulting product-specific recommendations, as dosing can vary widely based on the form and concentration of mycelium used.

Mechanism of action

Mycelium interacts with the environment primarily through enzymatic processes. It secretes various enzymes that break down complex organic materials, facilitating nutrient absorption. This decomposition process can lead to the release of bioactive compounds, which may exhibit antimicrobial, anti-inflammatory, and immunomodulatory effects. Some specific mycelium extracts have been shown to enhance immune function and have potential anti-tumor properties.

Pharmacodynamics

The pharmacodynamics of mycelium are largely influenced by its bioactive compounds, including polysaccharides, glycoproteins, and terpenes. These compounds can modulate immune responses, potentially enhancing the activity of immune cells such as macrophages and natural killer cells. Additionally, mycelium has been studied for its antioxidant properties, which may contribute to its protective effects against oxidative stress and inflammation within the body.

Pharmacokinetics

The pharmacokinetics of mycelium depend on its form of administration (e.g., extract, powder, or whole food) and the specific compounds being assessed. Generally, bioactive components from mycelium may be absorbed in the gastrointestinal tract, with effects varying based on their molecular weight and solubility. Metabolism and excretion pathways are not well-defined, as research on mycelium is ongoing, and many studies focus on its extracts rather than the whole organism.

Adverse effects

  • Gastrointestinal upset
  • Allergic reactions
  • Headaches

Precautions

  • Use with caution in individuals with known allergies to mushrooms or fungal products
  • Monitor for potential allergic reactions
  • Consult healthcare provider before use in individuals with underlying health conditions

Pregnancy

Limited data available; consult healthcare provider before use.

Breast-feeding

Limited data available; consult healthcare provider before use.

Storage

Store in a cool, dry place away from direct sunlight.

Formulations

  • Powdered mycelium
  • Capsules
  • Extracts

AI-synthesized from BNF references - general information only, not a substitute for professional medical advice or the current BNF. Verify doses with a pharmacist.

Clinical monograph: pantotrichum

Pantotrichum is not a recognized drug in the pharmacological literature, and no specific information is available regarding its use, mechanism, or pharmacokinetics. It is possible that the term refers to a compound or agent not widely acknowledged or documented in clinical settings.

Dosage

Children: Refer to relevant clinical guidelines or literature for appropriate dosing information.

Adults: Refer to relevant clinical guidelines or literature for appropriate dosing information.

Pregnancy

There is insufficient data regarding the safety of pantotrichum during pregnancy. It is advised to consult a healthcare professional before use.

Breast-feeding

There is limited information on the excretion of pantotrichum in breast milk. Caution is recommended, and a healthcare provider should be consulted.

Storage

Store in a cool, dry place, away from direct sunlight. Keep out of reach of children.

AI-synthesized from BNF references - general information only, not a substitute for professional medical advice or the current BNF. Verify doses with a pharmacist.

Clinical monograph: radix

Radix, often referring to herbal extracts from roots, has a variety of traditional and medicinal uses depending on the specific plant source. Commonly, radix preparations are utilized in herbal medicine for their potential therapeutic benefits, including anti-inflammatory, antioxidant, and immune-modulating properties. The exact composition and effects can vary significantly based on the specific radix used.

Indications

  • Anti-inflammatory effects
  • Antioxidant support
  • Immune system modulation
  • Support in chronic diseases
  • General wellness and health maintenance

Dosage

Children: Paediatric dosing for radix extracts should be approached with caution and is best determined by a healthcare provider, taking into account the child's age, weight, and health condition.

Adults: Dosage for radix extracts varies widely based on the specific herb and its intended use. It is advisable to refer to specific guidelines or consult with a healthcare professional for dosage recommendations.

Mechanism of action

The mechanisms of action for radix extracts are diverse and depend on the specific herb. Generally, these extracts may exert their effects through modulation of various signaling pathways, including the inhibition of pro-inflammatory cytokines, enhancement of antioxidant defenses, and regulation of immune cell activity. Many radix formulations contain bioactive compounds that interact with specific molecular targets, leading to physiological changes that contribute to their therapeutic effects.

Pharmacodynamics

Pharmacodynamics of radix extracts involves their interactions with biological systems. They may exhibit properties such as anti-inflammatory effects, reduction of oxidative stress, and modulation of cellular signaling pathways. The therapeutic effects often result from synergistic actions of multiple phytochemicals present in the extracts, which can influence various physiological processes.

Pharmacokinetics

The pharmacokinetics of radix extracts are largely dependent on the specific plant source and its constituents. Generally, these compounds are absorbed in the gastrointestinal tract, metabolized primarily by the liver, and excreted via urine or bile. The bioavailability of bioactive compounds can vary, influenced by factors such as the method of preparation, the presence of other food substances, and the individual’s metabolic rate.

Pregnancy

Lack of sufficient data on safety during pregnancy. Caution is advised.

Breast-feeding

Limited data available. Use with caution and consult a healthcare professional.

Storage

Store in a cool, dry place away from direct sunlight.

AI-synthesized from BNF references - general information only, not a substitute for professional medical advice or the current BNF. Verify doses with a pharmacist.

Clinical monograph: sinensis

Sinensis, often referred to in the context of traditional medicine, particularly in Traditional Chinese Medicine (TCM), is derived from the roots of the plant 'Panax ginseng'. This herbal remedy is primarily recognized for its adaptogenic properties, which help the body adapt to stress and exert a normalizing effect on bodily processes. It is used in various formulations to enhance energy, improve cognitive function, and support the immune system.

Indications

  • Fatigue
  • Cognitive impairment
  • Stress management
  • Immune system support
  • Physical endurance enhancement

Dosage

Children: Refer to established herbal guidelines or consult a healthcare professional for appropriate dosing.

Adults: Refer to established herbal guidelines or consult a healthcare professional for appropriate dosing.

Mechanism of action

The active compounds in Sinensis, particularly ginsenosides, are believed to modulate the immune system, enhance physical performance, and improve cognitive function. These compounds interact with multiple cellular pathways, including the modulation of nitric oxide production, antioxidant activity, and regulation of glucose metabolism, contributing to its adaptogenic effects.

Pharmacodynamics

Sinensis exhibits a range of pharmacodynamic effects, including stimulation of the central nervous system, enhancement of physical endurance, and immunomodulatory effects. Its adaptogenic properties help the body cope with stress, while its ability to enhance cognitive functions is attributed to its influence on neurotransmitter systems, particularly cholinergic and dopaminergic pathways.

Pharmacokinetics

The pharmacokinetics of Sinensis are characterized by its absorption, distribution, metabolism, and excretion (ADME) properties. After oral administration, ginsenosides are absorbed in the gastrointestinal tract, with peak plasma concentrations occurring within a few hours. They undergo extensive hepatic metabolism, primarily via cytochrome P450 enzymes. The elimination half-life varies, but metabolites are typically excreted through urine and feces.

Pregnancy

Limited data available; consult healthcare provider before use.

Breast-feeding

Consult healthcare provider before use, as safety is not well established.

Storage

Store in a cool, dry place, away from direct sunlight.

AI-synthesized from BNF references - general information only, not a substitute for professional medical advice or the current BNF. Verify doses with a pharmacist.

This drug in other countries

The same active ingredient registered across other registries we cover - including different brands.