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ANTI-FEVER ORAL SOLUTION

Radix Bupleuri

FDA/V.255-07095 Radix Bupleuri 150mg

What it does

Bupleuri is a herbal remedy often used for its potential benefits in supporting overall health and wellness.

Commonly used for: stress relief, anxiety reduction, supporting liver health

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Plain-language summary for general understanding - not medical advice. Always follow your pharmacist/doctor.

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Registration & product details

Registration no.
FDA/V.255-07095
Registration date
2025-07-16
Expiry date
2030-08-01
Status
Valid
Active ingredient
Radix Bupleuri
Dosage form
Radix Bupleuri
Strength
150mg
Pack size
-
Therapeutic class
-
Manufacturer / MAH
Aether Centre Biology Company
Country of origin
CHINA

Source: Food and Drugs Authority · fetched 2026-04-18 08:33:02 · updated 2026-10-20 04:00:14

Disclaimer: This information is sourced from Food and Drugs Authority (Ghana). Always consult a qualified healthcare professional before using any medication.

About bupleuri

Bupleuri is a herbal remedy often used for its potential benefits in supporting overall health and wellness.

What it treats

  • stress relief
  • anxiety reduction
  • supporting liver health

How it works

Bupleuri may help improve mood and reduce stress by supporting the body's natural balance.

Who it's for

It is generally used by adults looking for natural ways to manage stress and promote well-being.

AI-assisted summary grounded in BNF data - general information only, not medical advice. Always confirm with your pharmacist or doctor.

About radix

Radix is a herbal ingredient used in traditional medicine.

What it treats

  • general wellness
  • support for various health conditions

How it works

Radix is believed to support overall health and balance in the body.

Who it's for

This may be suitable for individuals looking for natural health support.

AI-assisted summary grounded in BNF data - general information only, not medical advice. Always confirm with your pharmacist or doctor.

Clinical monograph: bupleuri

Bupleuri, derived from the roots of the Bupleurum species, particularly Bupleurum chinense, is a traditional herbal remedy used in Asian medicine. It has been utilized for its potential anti-inflammatory, hepatoprotective, and immunomodulatory effects. The active compounds in Bupleuri, such as saikosaponins, are believed to contribute to its therapeutic properties, making it a popular choice for addressing conditions like liver disorders and respiratory issues.

Indications

  • Liver disorders
  • Chronic hepatitis
  • Inflammatory conditions
  • Respiratory infections
  • Immune system support

Dosage

Children: Paediatric dosing is not well established; consult established herbal guidelines or a healthcare provider for appropriate dosing in children.

Adults: Dosage varies depending on the formulation and intended use. Generally, standard doses in herbal medicine range from 9 to 30 grams of the dried root daily, often in divided doses.

Mechanism of action

Bupleuri exerts its effects primarily through the modulation of immune response and reduction of inflammation. Saikosaponins, the main active constituents, interact with various signaling pathways, including the inhibition of NF-κB activation, which plays a crucial role in inflammatory processes. This modulation helps in reducing symptoms related to inflammation and may protect liver cells from damage.

Pharmacodynamics

The pharmacodynamics of Bupleuri involve its ability to enhance liver function and promote bile secretion, as well as its anti-inflammatory effects. It has been shown to influence cytokine production, thereby modulating immune responses. The herb may also exhibit antioxidant properties, helping to reduce oxidative stress in the liver and other tissues.

Pharmacokinetics

The pharmacokinetics of Bupleuri are not extensively characterized in clinical studies, but it is generally believed that the bioactive compounds are absorbed in the gastrointestinal tract and metabolized in the liver. The elimination half-life and specific metabolic pathways are not well-defined, necessitating further research to clarify these aspects.

Pregnancy

Bupleuri is classified as possibly unsafe during pregnancy due to insufficient evidence of safety. Consult a healthcare provider before use.

Breast-feeding

Insufficient reliable information is available regarding the safety of bupleuri during breastfeeding. It is advisable to consult a healthcare provider.

Storage

Store in a cool, dry place away from direct sunlight. Keep out of reach of children.

AI-synthesized from BNF references - general information only, not a substitute for professional medical advice or the current BNF. Verify doses with a pharmacist.

Clinical monograph: radix

Radix, often referring to herbal extracts from roots, has a variety of traditional and medicinal uses depending on the specific plant source. Commonly, radix preparations are utilized in herbal medicine for their potential therapeutic benefits, including anti-inflammatory, antioxidant, and immune-modulating properties. The exact composition and effects can vary significantly based on the specific radix used.

Indications

  • Anti-inflammatory effects
  • Antioxidant support
  • Immune system modulation
  • Support in chronic diseases
  • General wellness and health maintenance

Dosage

Children: Paediatric dosing for radix extracts should be approached with caution and is best determined by a healthcare provider, taking into account the child's age, weight, and health condition.

Adults: Dosage for radix extracts varies widely based on the specific herb and its intended use. It is advisable to refer to specific guidelines or consult with a healthcare professional for dosage recommendations.

Mechanism of action

The mechanisms of action for radix extracts are diverse and depend on the specific herb. Generally, these extracts may exert their effects through modulation of various signaling pathways, including the inhibition of pro-inflammatory cytokines, enhancement of antioxidant defenses, and regulation of immune cell activity. Many radix formulations contain bioactive compounds that interact with specific molecular targets, leading to physiological changes that contribute to their therapeutic effects.

Pharmacodynamics

Pharmacodynamics of radix extracts involves their interactions with biological systems. They may exhibit properties such as anti-inflammatory effects, reduction of oxidative stress, and modulation of cellular signaling pathways. The therapeutic effects often result from synergistic actions of multiple phytochemicals present in the extracts, which can influence various physiological processes.

Pharmacokinetics

The pharmacokinetics of radix extracts are largely dependent on the specific plant source and its constituents. Generally, these compounds are absorbed in the gastrointestinal tract, metabolized primarily by the liver, and excreted via urine or bile. The bioavailability of bioactive compounds can vary, influenced by factors such as the method of preparation, the presence of other food substances, and the individual’s metabolic rate.

Pregnancy

Lack of sufficient data on safety during pregnancy. Caution is advised.

Breast-feeding

Limited data available. Use with caution and consult a healthcare professional.

Storage

Store in a cool, dry place away from direct sunlight.

AI-synthesized from BNF references - general information only, not a substitute for professional medical advice or the current BNF. Verify doses with a pharmacist.

This drug in other countries

The same active ingredient registered across other registries we cover - including different brands.