Valid Ghana · FDA Ghana

AQUAREST POWDER

SACCHAROMYCES BOULARDI

FDA/SD.243-040609 SACCHAROMYCES BOULARDI 803mg

What it does

Boulardi is a type of probiotic that helps maintain gut health.

Commonly used for: diarrhea, irritable bowel syndrome (IBS), gut health support

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Plain-language summary for general understanding - not medical advice. Always follow your pharmacist/doctor.

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Registration & product details

Registration no.
FDA/SD.243-040609
Registration date
2024-04-16
Expiry date
2027-05-01
Status
Valid
Active ingredient
SACCHAROMYCES BOULARDI
Strength
803mg
Pack size
-
Therapeutic class
-
Manufacturer / MAH
Sai Mirra Innopharm
Country of origin
India

Source: Food and Drugs Authority · fetched 2026-04-18 08:37:13 · updated 2026-09-18 04:00:04

Disclaimer: This information is sourced from Food and Drugs Authority (Ghana). Always consult a qualified healthcare professional before using any medication.

About boulardi

Boulardi is a type of probiotic that helps maintain gut health.

What it treats

  • diarrhea
  • irritable bowel syndrome (IBS)
  • gut health support

How it works

Boulardi works by restoring the balance of good bacteria in the gut, which can help improve digestion and prevent diarrhea.

Who it's for

It is suitable for adults and children needing support for their digestive health.

AI-assisted summary grounded in BNF data - general information only, not medical advice. Always confirm with your pharmacist or doctor.

About saccharomyces

Saccharomyces is a type of yeast used as a dietary supplement to support digestive health.

What it treats

  • digestive issues
  • diarrhea
  • irritable bowel syndrome (IBS)
  • promoting gut health

How it works

Saccharomyces helps balance good bacteria in the gut, which can improve digestion and overall gut health.

Who it's for

Adults and children experiencing digestive problems or those looking to support their gut health.

AI-assisted summary grounded in BNF data - general information only, not medical advice. Always confirm with your pharmacist or doctor.

Clinical monograph: boulardi

Boulardi, commonly referred to as Saccharomyces boulardii, is a probiotic yeast strain that is used to support gastrointestinal health. It is known for its ability to restore the natural flora of the gut and is often utilized in the management of various gastrointestinal disorders. Saccharomyces boulardii is particularly noted for its role in the prevention and treatment of antibiotic-associated diarrhea and for its potential benefits in managing inflammatory bowel diseases.

Indications

  • Antibiotic-associated diarrhea
  • Clostridium difficile infection
  • Inflammatory bowel disease
  • Irritable bowel syndrome
  • Traveler's diarrhea

Dosage

Children: Refer to product-specific guidelines or consult a healthcare professional for appropriate dosing.

Adults: Refer to product-specific guidelines or consult a healthcare professional for appropriate dosing.

Mechanism of action

Saccharomyces boulardii exerts its beneficial effects through multiple mechanisms. It enhances the intestinal barrier function, promoting the integrity of the gut mucosa. It also modulates immune responses by stimulating the production of secretory immunoglobulin A (sIgA) and other immune mediators. Additionally, it produces short-chain fatty acids and other metabolites that can inhibit pathogenic bacteria and promote the growth of beneficial gut flora.

Pharmacodynamics

The pharmacodynamics of Saccharomyces boulardii involve its ability to adhere to the intestinal mucosa, thereby preventing the adhesion of pathogenic microorganisms. It also influences the gut microbiota composition and acts to reduce inflammation within the gastrointestinal tract. The probiotic properties contribute to the maintenance of intestinal health and the prevention of dysbiosis.

Pharmacokinetics

Saccharomyces boulardii is not absorbed systemically; instead, it acts locally within the gastrointestinal tract. Following oral administration, it survives the acidic environment of the stomach and reaches the intestines where it colonizes temporarily. The yeast is eventually excreted in the feces, and its effects can be observed shortly after administration, generally within 1 to 3 days.

Adverse effects

  • Bloating
  • Gas
  • Constipation
  • Allergic reactions

Precautions

  • Use with caution in immunocompromised patients
  • Patients with severe underlying health conditions should consult a healthcare provider before use

Pregnancy

Generally considered safe, but consult a healthcare provider before use.

Breast-feeding

Generally considered safe, but consult a healthcare provider before use.

Storage

Store in a cool, dry place away from direct sunlight. Keep out of reach of children.

Formulations

  • Capsules
  • Powder

AI-synthesized from BNF references - general information only, not a substitute for professional medical advice or the current BNF. Verify doses with a pharmacist.

Clinical monograph: saccharomyces

Saccharomyces, commonly known as brewer's or baker's yeast, is a genus of fungi used for its fermentative properties. It is primarily utilized in the production of alcoholic beverages, baking, and as a dietary supplement due to its probiotic effects. Saccharomyces boulardii, a specific strain, is recognized for its beneficial effects on gastrointestinal health.

Indications

  • Antibiotic-associated diarrhea
  • Acute infectious diarrhea
  • Chronic diarrhea in conditions like irritable bowel syndrome
  • Maintenance of gut flora during antibiotic therapy
  • Prevention of traveler's diarrhea

Dosage

Children: Refer to specific product guidelines for paediatric dosages, as they may vary depending on the formulation and age of the child.

Adults: Refer to specific product guidelines for recommended adult dosages, as they may vary depending on the formulation.

Mechanism of action

Saccharomyces boulardii exerts its effects by promoting gut health through various mechanisms. It enhances the intestinal barrier function, modulates local immune responses, and inhibits the growth of pathogenic bacteria. It also produces short-chain fatty acids and aids in the maintenance of gut microbiota balance, which can help in reducing diarrhea and improving gut health.

Pharmacodynamics

The pharmacodynamics of Saccharomyces involve its ability to adhere to intestinal mucosa, which helps in restoring the normal flora of the gut. It has been shown to reduce the duration and severity of diarrhea, particularly in cases of antibiotic-associated diarrhea and infectious diarrhea. Additionally, it may enhance the absorption of nutrients and support the immune system.

Pharmacokinetics

Saccharomyces boulardii is generally not absorbed systemically; instead, it acts locally in the gastrointestinal tract. It survives passage through the stomach and colonizes the intestines, where it exerts its beneficial effects. The viability of Saccharomyces is influenced by factors such as pH, temperature, and the presence of other gastrointestinal microorganisms. Its effects are typically observed within a few days of administration.

Adverse effects

  • Gastrointestinal upset
  • Bloating
  • Gas
  • Diarrhea

Interactions

  • May interact with antifungal medications
  • Potential interactions with immunosuppressive drugs

Precautions

  • Caution in patients with compromised immune systems
  • Use with caution in patients with a history of yeast allergies

Pregnancy

Limited data available, consult healthcare provider before use.

Breast-feeding

Generally considered safe, but consult healthcare provider.

Storage

Store in a cool, dry place, away from direct sunlight.

Formulations

  • Capsules
  • Tablets
  • Powder for oral suspension
  • Granules

AI-synthesized from BNF references - general information only, not a substitute for professional medical advice or the current BNF. Verify doses with a pharmacist.

This drug in other countries

The same active ingredient registered across other registries we cover - including different brands.