Registered Malawi · PMRA

RUBIA*CORDIFOLIA 250MG CAPSULE

RUBIA CORDIFOLIA

PMPB/PL349/15 CAPSULE

What it does

Cordifolia is a natural substance often used for its potential health benefits.

Commonly used for: general wellness, supporting immune function, reducing inflammation

Read more in plain English ↓

Plain-language summary for general understanding - not medical advice. Always follow your pharmacist/doctor.

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Medicine sourcing is available in Kenya only. We don't sell or dispense medicines - licensed pharmacies do.

Sourcing - Kenya only

Registration & product details

Registration no.
PMPB/PL349/15
Registration date
04/07/2008
Expiry date
30/06/2010
Status
Registered
Active ingredient
RUBIA CORDIFOLIA
Dosage form
CAPSULE
Strength
-
Pack size
-
Therapeutic class
-
Manufacturer / MAH
-
Applicant / LTR
-
Country of origin
-

Source: Pharmacy and Medicines Regulatory Authority · fetched 2026-04-21 17:37:41 · updated 2026-09-22 04:33:03

Disclaimer: This information is sourced from Pharmacy and Medicines Regulatory Authority (Malawi). Always consult a qualified healthcare professional before using any medication.

About cordifolia

Cordifolia is a natural substance often used for its potential health benefits.

What it treats

  • general wellness
  • supporting immune function
  • reducing inflammation

How it works

Cordifolia is believed to help the body by supporting various functions, including boosting the immune system and reducing inflammation.

Who it's for

Cordifolia may be suitable for adults looking for natural support for their overall health.

AI-assisted summary grounded in BNF data - general information only, not medical advice. Always confirm with your pharmacist or doctor.

About rubia

Rubia is a natural product used for various health conditions.

What it treats

  • skin conditions
  • inflammation
  • digestive issues

How it works

Rubia may help by reducing inflammation and supporting skin health.

Who it's for

Rubia can be used by adults and children for certain skin and digestive conditions.

AI-assisted summary grounded in BNF data - general information only, not medical advice. Always confirm with your pharmacist or doctor.

Clinical monograph: cordifolia

Cordifolia, commonly known as 'Indian ginseng' or 'Withania somnifera', is a medicinal herb used in traditional medicine for its adaptogenic properties. It is believed to enhance physical and mental performance, reduce stress, and support overall health. Cordifolia is known for its potential benefits in managing anxiety, improving cognitive function, and boosting immunity.

Indications

  • Stress relief
  • Anxiety management
  • Cognitive enhancement
  • Improvement of physical performance
  • Support for immune function

Dosage

Children: Refer to established herbal guidelines or consult with a healthcare provider for appropriate dosing.

Adults: Refer to established herbal guidelines or consult with a healthcare provider for appropriate dosing.

Mechanism of action

The primary active compounds in Cordifolia are known as withanolides, which exhibit a variety of pharmacological effects. These compounds modulate several signaling pathways, including the inhibition of the nuclear factor kappa B (NF-kB) and the activation of the AMP-activated protein kinase (AMPK). This modulation leads to anti-inflammatory, antioxidant, and neuroprotective effects. Additionally, withanolides may influence neurotransmitter levels, thereby aiding in mood regulation and cognitive enhancement.

Pharmacodynamics

Cordifolia demonstrates adaptogenic effects, helping the body resist stressors of various kinds. It has been shown to improve physical endurance, enhance memory and cognitive function, and exert a calming effect on the nervous system. The herb also exhibits immunomodulatory properties, promoting a healthy immune response while reducing inflammation.

Pharmacokinetics

The pharmacokinetics of Cordifolia are not extensively studied compared to conventional pharmaceuticals. However, it is generally understood that withanolides are absorbed in the gastrointestinal tract, undergo hepatic metabolism, and are excreted primarily through urine and feces. The bioavailability of these compounds can be affected by various factors, including formulation and dosage form.

Pregnancy

Insufficient data available; consult healthcare provider.

Breast-feeding

Insufficient data available; consult healthcare provider.

Storage

Store in a cool, dry place away from direct sunlight.

AI-synthesized from BNF references - general information only, not a substitute for professional medical advice or the current BNF. Verify doses with a pharmacist.

Clinical monograph: rubia

Rubia, commonly known as Rubia tinctorum, is a perennial herb belonging to the family Rubiaceae. Traditionally used in herbal medicine, it has various applications including its use as a dye and in the treatment of certain health conditions due to its bioactive compounds. The plant contains anthraquinones and other phytochemicals that exhibit potential therapeutic effects.

Indications

  • Anti-inflammatory conditions
  • Antimicrobial applications
  • Antioxidant support
  • Traditional dyeing agent

Dosage

Children: Refer to established herbal dosage guidelines or consult with a healthcare professional.

Adults: Refer to established herbal dosage guidelines or consult with a healthcare professional.

Mechanism of action

The active compounds in Rubia tinctorum, particularly anthraquinones, are believed to exert their effects through several mechanisms. These include inhibition of certain enzymes, modulation of inflammatory pathways, and interaction with cellular signaling pathways. The compounds may also exhibit antioxidant properties, contributing to their therapeutic potential.

Pharmacodynamics

Rubia tinctorum has been shown to possess anti-inflammatory, antimicrobial, and antioxidant properties. The anthraquinones can influence various biological pathways, potentially leading to the modulation of immune responses and the reduction of oxidative stress in cells. Its effects may vary based on the dosage and preparation used.

Pharmacokinetics

The pharmacokinetics of Rubia tinctorum have not been extensively studied. However, it is understood that the bioavailability of its active compounds may be influenced by factors such as their solubility and stability in the gastrointestinal tract. Metabolism typically occurs in the liver, and excretion is primarily via the kidneys. Specific half-life and elimination data are not well documented.

Pregnancy

There is limited data on the safety of rubia during pregnancy. It is advisable to avoid use unless the potential benefits outweigh the risks.

Breast-feeding

The excretion of rubia in human milk is unknown. Caution is advised when used during breastfeeding.

Storage

Store in a cool, dry place, away from direct sunlight. Keep out of reach of children.

AI-synthesized from BNF references - general information only, not a substitute for professional medical advice or the current BNF. Verify doses with a pharmacist.

This drug in other countries

The same active ingredient registered across other registries we cover - including different brands.